Literature DB >> 7164945

Release of platelet-activating factor (PAF-acether) and 2-lyso PAF-acether from three cell types.

J Benveniste, R Roubin, M Chignard, E Jouvin-Marche, J P Le Couedic.   

Abstract

The release and formation of PAF-acether and of its deacetylated precursor (2-lyso PAF-acether) have been determined on mouse macrophages (M phi), human polymorphonuclear neutrophils (PMN) and rabbit platelets using specific secretagogue stimuli in the same experimental conditions. It was found that as opposed to M phi, PMN and platelets were good releasers of PAF-acether. However, the total amount of PAF-acether formed by M phi and PMN was larger than that formed by platelets. The total amount of 2-lyso PAF-acether varied also for the three cell types, with platelets being by far the best producer. Calculation of the amount of PAF-acether formed from 2-lyso PAF-acether indicated that M phi and PMN possess a higher acetylating ability than platelets.

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Year:  1982        PMID: 7164945     DOI: 10.1007/bf01965088

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  20 in total

1.  Structural analysis of purified platelet-activating factor by lipases.

Authors:  J Benveniste; J P Le Couedic; J Polonsky; M Tence
Journal:  Nature       Date:  1977-09-08       Impact factor: 49.962

2.  The role of platelet-activating factor in platelet aggregation.

Authors:  M Chignard; J P Le Couedic; M Tence; B B Vargaftig; J Benveniste
Journal:  Nature       Date:  1979-06-28       Impact factor: 49.962

3.  Platelet-activating factor (PAF-acether) and macrophages. II. Phagocytosis-associated release of PAF-acether from rat peritoneal macrophages.

Authors:  J M Mencia-Huerta; J Benveniste
Journal:  Cell Immunol       Date:  1981-01-15       Impact factor: 4.868

4.  Release of 1-O-alkylglyceryl 3-phosphorylcholine, O-deacetyl platelet-activating factor, from leukocytes: chemical ionization mass spectrometry of phospholipids.

Authors:  J Polonsky; M Tencé; P Varenne; B C Das; J Lunel; J Benveniste
Journal:  Proc Natl Acad Sci U S A       Date:  1980-12       Impact factor: 11.205

5.  Structural analogs of platelet-activating factor (PAF-acether).

Authors:  M Tence; E Coeffier; F Heymans; J Polonsky; J J Godfroid; J Benveniste
Journal:  Biochimie       Date:  1981 Aug-Sep       Impact factor: 4.079

6.  Release of platelet-activating factor (PAF-acether) and leukotrienes C and D from inflammatory macrophages.

Authors:  R Roubin; J M Mencia-Huerta; J Benveniste
Journal:  Eur J Immunol       Date:  1982-02       Impact factor: 5.532

7.  A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).

Authors:  M L Blank; T Lee; V Fitzgerald; F Snyder
Journal:  J Biol Chem       Date:  1981-01-10       Impact factor: 5.157

8.  Release of slow reacting substance of anaphylaxis (SRS-A) from human leukocytes by the calcium ionophore A23187.

Authors:  M C Conroy; R P Orange; L M Lichtenstein
Journal:  J Immunol       Date:  1976-06       Impact factor: 5.422

9.  Release, purification, and characterization of platelet-activating factor (PAF).

Authors:  V Tencé; J Polonsky; J P Le Couedic; M J Benveniste
Journal:  Biochimie       Date:  1980       Impact factor: 4.079

10.  Is platelet-activating factor (PAF-acether) synthesis by murine peritoneal cells (PC) a two-step process?

Authors:  J M Mencia-Huerta; E Ninio; R Roubin; J Benveniste
Journal:  Agents Actions       Date:  1981-12
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  11 in total

1.  Quantitation by radioimmunoassay of PAF in human saliva.

Authors:  S J Cooney; M A Smal; B A Baldo
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

2.  Inflammatory responses to intradermal injection of platelet activating factor, histamine and prostaglandin E2 in healthy volunteers: a double blind investigation.

Authors:  D G Sciberras; M M Goldenberg; J A Bolognese; I James; N S Baber
Journal:  Br J Clin Pharmacol       Date:  1987-12       Impact factor: 4.335

3.  PAF-acether induced cardiac dysfunction in the isolated perfused guinea pig heart.

Authors:  G L Stahl; D J Lefer; A M Lefer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-10       Impact factor: 3.000

4.  Effect of synthetic phospholipids on platelet aggregation and serotonin release.

Authors:  U Söling; H Eibl; G A Nagel; C Unger
Journal:  Lipids       Date:  1987-11       Impact factor: 1.880

5.  Platelet-activating factor (PAF-acether) formation in rat basophilic leukemia cells stimulated by ionophore A23187.

Authors:  M Hirafuji; J F Nave
Journal:  Agents Actions       Date:  1987-10

Review 6.  Platelet-activating factor and the cytokine network in inflammatory processes.

Authors:  B Bonavida; J M Mencia-Huerta
Journal:  Clin Rev Allergy       Date:  1994

7.  Pathophysiological mechanisms of sudden death induced by platelet activating factor.

Authors:  A M Lefer; H F Müller; J B Smith
Journal:  Br J Pharmacol       Date:  1984-09       Impact factor: 8.739

8.  Inhibition of PAF-acether effects on isolated guinea pig hearts by zinc ions (Zn2+).

Authors:  A Evangelou; V Kalfakakou; J Benveniste; B Arnoux
Journal:  Biol Trace Elem Res       Date:  1995-10       Impact factor: 3.738

9.  Comparison of cardiac and hemodynamic effects of platelet-activating factor-acether and leukotriene D4 in anesthetized dogs.

Authors:  V B Fiedler; M Mardin; T S Abram
Journal:  Basic Res Cardiol       Date:  1987 Mar-Apr       Impact factor: 17.165

10.  Ischemia aggravating effects of platelet-activating factor in acute myocardial ischemia.

Authors:  I Leprán; A M Lefer
Journal:  Basic Res Cardiol       Date:  1985 Mar-Apr       Impact factor: 17.165

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