Literature DB >> 7164934

The lack of effect of histamine on spontaneous activity in the isolated human myometrium.

S Dai, C W Ogle, P M Leung.   

Abstract

The effects of histamine on the spontaneous activity of the isolated human myometrium were studied. Both the frequency and force of contractions of the muscle strips were not significantly altered by histamine. The presence of either a histamine H1- or H2-receptor antagonist in the organ bath did not significantly change the responses of the uterine muscle to histamine. These findings suggest that histamine has negligible effects on the human myometrium, possibly due to the absence, or paucity, of histamine receptors.

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Year:  1982        PMID: 7164934     DOI: 10.1007/bf01965068

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  8 in total

1.  Plain-muscle stimulants in extracts of menstrual fluid and of endometrial curettings.

Authors:  P L CHAMBERS; V R PICKLES
Journal:  J Physiol       Date:  1958-11-10       Impact factor: 5.182

2.  Effect of magnesium ion on the response of the rat uterus to neurohypophysial hormones and analogues.

Authors:  R A MUNSICK
Journal:  Endocrinology       Date:  1960-03       Impact factor: 4.736

3.  In vitro studies of the motility of the human uterus. III. The effects of adrenaline, noradrenaline and acetylcholine on the spontaneous motility in different parts of the pregnant and non-pregnant uterus.

Authors:  F SANDBERG; A INGELMAN-SUNDBERG; L LINDGREN; G RYDEN
Journal:  J Obstet Gynaecol Br Emp       Date:  1958-12

4.  In vitro studies of the motility of the human uterus. I. The spontaneous motility in different parts of the non-pregnant uterus during the sexual cycle and in the menopause and its correlation with the actomyosin content.

Authors:  F SANDBERG; A INGELMAN-SUNDBERG; L LINDGREN; G RYDEN
Journal:  J Obstet Gynaecol Br Emp       Date:  1957-06

5.  Response to isoprenaline in the human pregnant and non-pregnant myometrium.

Authors:  K Lossius
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1976-08

6.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

7.  The effect of isoprenaline on the contraction of smooth muscle produced by histamine, acetylcholine or other agents.

Authors:  J B Farmer; D N Lehrer
Journal:  J Pharm Pharmacol       Date:  1966-10       Impact factor: 3.765

8.  The effect of indomethacin on spontaneous activity in the isolated human myometrium and on the response to oxytocin and prostaglandin.

Authors:  D B Garrioch
Journal:  Br J Obstet Gynaecol       Date:  1978-01
  8 in total
  1 in total

1.  Effect of histamine and histamine analogues on human isolated myometrial strips.

Authors:  M I Martínez-Mir; L Estañ; F J Morales-Olivas; E Rubio
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

  1 in total

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