Literature DB >> 7163966

Bioadhesive and histotoxic properties of ethyl-2-cyanoacrylate.

B J Zumpano, L R Jacobs, J B Hall, G Margolis, E Sachs.   

Abstract

Ethyl-2-cyanoacrylate was applied to the cortex of rabbits to evaluate its bioadhesive and histotoxic behavior. The animals were killed at 4 or 10 days. Half of the animals were pretreated with dexamethasone. Our results indicate that the application of ethyl-2-cyanoacrylate to brain tissue produced severe superficial cortical necrosis but not bioadhesion. Pretreatment with steroids did not provide a significant protective effect.

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Year:  1982        PMID: 7163966     DOI: 10.1016/0090-3019(82)90186-0

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  1 in total

1.  Skull base cerebrospinal fluid leakage control with a fibrin-based composite tissue adhesive.

Authors:  J P Rock; D H Sierra; F Castro-Moure; F Jiang
Journal:  Skull Base Surg       Date:  1996
  1 in total

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