Literature DB >> 7161792

Monosodium urate crystals in asymptomatic knee joints.

T P Gordon, J V Bertouch, B R Walsh, P M Brooks.   

Abstract

Monosodium urate (MSU) crystals were shown in synovial (SF) fluid taken from the asymptomatic knee joints of 11 out of 13 patients with tophaceous gout. Intracellular crystals were identified in some cases. Examination of synovial biopsies taken concurrently revealed MSU crystals in 2 out of 6 cases. The results show that MSU crystals can be found in SF and synovium in the absence of acute gout. This implies that additional factors are important in the pathogenesis of gouty inflammation.

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Year:  1982        PMID: 7161792

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  4 in total

1.  Role of ultrasound and other advanced imaging in the diagnosis and management of gout.

Authors:  Ralf G Thiele
Journal:  Curr Rheumatol Rep       Date:  2011-04       Impact factor: 4.592

2.  Lipoproteins containing apoprotein B are a major regulator of neutrophil responses to monosodium urate crystals.

Authors:  R Terkeltaub; L K Curtiss; A J Tenner; M H Ginsberg
Journal:  J Clin Invest       Date:  1984-06       Impact factor: 14.808

3.  Crystal deposition in the knee and great toe joints of asymptomatic gout patients.

Authors:  T D Kennedy; C S Higgens; D F Woodrow; J T Scott
Journal:  J R Soc Med       Date:  1984-09       Impact factor: 5.344

4.  Lack of correlation between in vitro and in vivo effects of low density lipoprotein on the inflammatory activity of monosodium urate crystals.

Authors:  T P Gordon; P Clifton; M J James; P J Roberts-Thomson
Journal:  Ann Rheum Dis       Date:  1986-08       Impact factor: 19.103

  4 in total

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