Literature DB >> 7161564

All-trans-retinoic acid: measurement of reference values in human serum by high performance liquid chromatography.

A P De Leenheer, W E Lambert, I Claeys.   

Abstract

A quantitative determination of physiological levels of all-trans-retinoic acid (vitamin A acid) in human serum has been developed. A double-phase extraction of 3.5 ml of serum followed by a specific and sensitive high performance liquid chromatography procedure allowed measurement of levels down to 1 ng/ml. Serum concentrations in 37 fasting volunteers ranged from 2.7 to 4.2 ng/ml and fitted a normal-Gaussian distributional shape with a mean value of 3.5 ng/ml and SD of 0.4 ng/ml, as demonstrated by the Kolmogorov-Smirnov test.

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Year:  1982        PMID： 7161564

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


  24 in total

1.  UVA/B exposure promotes the biosynthesis of dehydroretinol in cultured human keratinocytes.

Authors:  Juliana I Tafrova; Adriana Pinkas-Sarafova; Erik Stolarzewicz; Kathlyn A Parker; Marcia Simon
Journal:  Mol Cell Biochem       Date:  2012-02-04       Impact factor: 3.396

2.  Myeloid cell leukaemia 1 has a vital role in retinoic acid-mediated protection of Toll-like receptor 9-stimulated B cells from spontaneous and DNA damage-induced apoptosis.

Authors:  Kristine L Holm; Randi L Indrevaer; June Helen Myklebust; Arne Kolstad; Jan Øivind Moskaug; Elin H Naderi; Heidi K Blomhoff
Journal:  Immunology       Date:  2016-07-25       Impact factor: 7.397

Review 3.  Metabolites: deciphering the molecular language between DCs and their environment.

Authors:  Lucía Minarrieta; Peyman Ghorbani; Tim Sparwasser; Luciana Berod
Journal:  Semin Immunopathol       Date:  2016-12-05       Impact factor: 9.623

4.  Inhibition of activation-induced apoptosis of thymocytes by all-trans- and 9-cis-retinoic acid is mediated via retinoic acid receptor alpha.

Authors:  Z Szondy; U Reichert; J M Bernardon; S Michel; R Tóth; E Karászi; L Fésüs
Journal:  Biochem J       Date:  1998-05-01       Impact factor: 3.857

5.  Demonstration of retinoic acid isomers in human urine under physiological conditions.

Authors:  W E Lambert; A P De Leenheer
Journal:  Experientia       Date:  1985-03-15

6.  Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells.

Authors:  Qiuyan Chen; A Catharine Ross
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-10       Impact factor: 11.205

7.  All-trans-retinoic acid distribution and metabolism in vitamin A-marginal rats.

Authors:  Christopher J Cifelli; A Catharine Ross
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2006-08       Impact factor: 4.052

8.  Liver-specific cytochrome P450 CYP2C22 is a direct target of retinoic acid and a retinoic acid-metabolizing enzyme in rat liver.

Authors:  Linxi Qian; Reza Zolfaghari; A Catharine Ross
Journal:  J Lipid Res       Date:  2010-02-10       Impact factor: 5.922

9.  Expression of human all-trans-retinoic acid receptor beta and its ligand-binding domain in Escherichia coli.

Authors:  M Berggren Söderlund; G Johannesson; G Fex
Journal:  Biochem J       Date:  1995-05-15       Impact factor: 3.857

10.  Isomerization of all-trans-retinoic acid to 9-cis-retinoic acid.

Authors:  J Urbach; R R Rando
Journal:  Biochem J       Date:  1994-04-15       Impact factor: 3.857
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