Literature DB >> 7158602

Design, development and test results of a horizontal flow inhalation toxicology facility.

D R Hemenway, S M MacAskill.   

Abstract

A horizontal flow chamber was developed for the purposes of conducting inhalation toxicology research. The chamber utilizes a unique diffuser system and pre-mixing of contaminants to achieve uniform exposure. The use of fecal catch pans eliminates exposure of animals to fecal debris from overhead animals. The chamber performance shows a rapid equilibrium in startup and shutdown.

Mesh:

Year:  1982        PMID: 7158602     DOI: 10.1080/15298668291410738

Source DB:  PubMed          Journal:  Am Ind Hyg Assoc J        ISSN: 0002-8894


  8 in total

1.  Asbestos causes translocation of p65 protein and increases NF-kappa B DNA binding activity in rat lung epithelial and pleural mesothelial cells.

Authors:  Y M Janssen; K E Driscoll; B Howard; T R Quinlan; M Treadwell; A Barchowsky; B T Mossman
Journal:  Am J Pathol       Date:  1997-08       Impact factor: 4.307

2.  Alveolar type II cell response in rats exposed to aerosols of alpha-cristobalite.

Authors:  R B Low; K O Leslie; D R Hemenway; M Absher; K B Adler; M S Giancola; P M Vacek
Journal:  Am J Pathol       Date:  1990-04       Impact factor: 4.307

3.  Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice.

Authors:  R F Robledo; S A Buder-Hoffmann; A B Cummins; E S Walsh; D J Taatjes; B T Mossman
Journal:  Am J Pathol       Date:  2000-04       Impact factor: 4.307

4.  Biphasic cellular and tissue response of rat lungs after eight-day aerosol exposure to the silicon dioxide cristobalite.

Authors:  M P Absher; L Trombley; D R Hemenway; R M Mickey; K O Leslie
Journal:  Am J Pathol       Date:  1989-06       Impact factor: 4.307

5.  Increased manganese superoxide dismutase protein in type II epithelial cells of rat lungs after inhalation of crocidolite asbestos or cristobalite silica.

Authors:  J A Holley; Y M Janssen; B T Mossman; D J Taatjes
Journal:  Am J Pathol       Date:  1992-08       Impact factor: 4.307

6.  Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos.

Authors:  T R Quinlan; K A BéruBé; J P Marsh; Y M Janssen; P Taishi; K O Leslie; D Hemenway; P T O'Shaughnessy; P Vacek; B T Mossman
Journal:  Am J Pathol       Date:  1995-09       Impact factor: 4.307

7.  Interleukin-12 is not essential for silicosis in mice.

Authors:  Gerald S Davis; Linda M Pfeiffer; David R Hemenway; Mercedes Rincon
Journal:  Part Fibre Toxicol       Date:  2006-01-05       Impact factor: 9.400

8.  Pleural macrophage recruitment and activation in asbestos-induced pleural injury.

Authors:  N Choe; S Tanaka; W Xia; D R Hemenway; V L Roggli; E Kagan
Journal:  Environ Health Perspect       Date:  1997-09       Impact factor: 9.031

  8 in total

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