Literature DB >> 7157463

A high pressure liquid chromatographic procedure for monitoring 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea levels in body fluids.

B Caddy, O R Idowu, J F Stuart.   

Abstract

A reverse phase high pressure liquid chromatographic method has been developed for the analysis of 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) levels present in body fluids. A value obtained for the plasma half-life for a single patient indicates that this may be larger than hitherto expected.

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Year:  1982        PMID: 7157463     DOI: 10.1097/00007691-198212000-00010

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN: 0163-4356            Impact factor:   3.681


  1 in total

1.  Pharmacokinetics of tauromustine in cancer patients. Phase I studies.

Authors:  P O Gunnarsson; J Vibe-Petersen; J S Macpherson; P S Warrington; J Polacek; M Ellman; H H Hansen; J F Smyth
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

  1 in total

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