Literature DB >> 7153212

Structural study on gangliosides from rat liver and erythrocytes.

C Rokukawa, Y Kushi, K Ueno, S Handa.   

Abstract

Gangliosides were isolated from rat liver and erythrocytes by chromatography on columns of DEAE-Sephadex and Iatrobeads, and finally purified by preparative TLC. The chemical structures of the purified components were studied by carbohydrate analysis, methylation analysis, sialidase treatment, fatty acid analysis and direct mass spectrometry. In rat liver, gangliosides GM3, GM1, GD3, GD1a, GD1b, and GT1b were identified. Gangliosides in rat erythrocytes were characterized as GM1, fucosyl-GM1, and GD1a. Sialic acid was the N-acetyl type only and lignoceric acid was the main fatty acid in all components of rat liver and erythrocytes.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7153212     DOI： 10.1093/oxfordjournals.jbchem.a134072

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  3 in total

Review 1.  Sphingolipidomics: methods for the comprehensive analysis of sphingolipids.

Authors:  Christopher A Haynes; Jeremy C Allegood; Hyejung Park; M Cameron Sullards
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-12-31       Impact factor: 3.205

2.  The N-acetylgalactosamine residue of exogenous GM2 ganglioside is recycled for glycoconjugate biosynthesis in rat liver.

Authors:  M Trinchera; R Ghidoni; L Greggia; G Tettamanti
Journal:  Biochem J       Date:  1990-02-15       Impact factor: 3.857

3.  beta 1-4N-acetylgalactosaminyltransferase can synthesize both asialoglycosphingolipid GM2 and glycosphingolipid GM2 in vitro and in vivo: isolation and characterization of a beta 1-4N-acetylgalactosaminyltransferase cDNA clone from rat ascites hepatoma cell line AH7974F.

Authors:  J K Hidari; S Ichikawa; K Furukawa; M Yamasaki; Y Hirabayashi
Journal:  Biochem J       Date:  1994-11-01       Impact factor: 3.857
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.