Literature DB >> 7153072

[Vitamin A concentration in plasma and ability to hear in patients with chronic alcoholic liver diseases].

E Löhle, J Schölmerich, J P Vuilleumier, E Köttgen.   

Abstract

59 patients with chronic alcoholic liver disease and with negative history of ear infection, noise exposure, head injury, use of streptomycin and without hereditary deafness underwent a basic audiologic examination. In all age groups we found a depression of the pure tone threshold on from 2,000 Hz and compared to a control group and to the norm curves (Spoor 1966). Following the Carhart-test and the acoustic facial reflex there were always signs of cochlear lesions. Fifty per cent of the alcoholics in the Carhart tone decay test showed a depression of the threshold between 10 and 30 dB. The concentration of vitamin A, RBP, beta-Carotin and zinc in the blood measured at the same time were diminished. Considering recent electron microscopic findings on the pattern of the inner ear of young rats following vitamin A deficit we suppose that the vitamin A deficit in the alcoholics leads to poor hearing.

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Year:  1982        PMID: 7153072

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  2 in total

Review 1.  [Vitamin A and the ear. Review of the literature].

Authors:  H K Biesalski
Journal:  Z Ernahrungswiss       Date:  1984-06

2.  The influence of chronic vitamin A deficiency on human and animal ears.

Authors:  E Löhle
Journal:  Arch Otorhinolaryngol       Date:  1982
  2 in total

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