Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis.

Literature DB >> 7152676

Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis.

N R Lynch, L Yarzábal, O Verde, J L Avila, H Monzon, J Convit.

Abstract

Delayed-type hypersensitivity (DTH) and both total and specific immunoglobulin E (IgE) antibody levels were studied during an outbreak of American cutaneous leishmaniasis. Direct correlations were detected between DTH reactivity and either age or the period of evolution of the infection, and a clear association with sex (strongest response in females) was observed. Extremely high, age-dependent, total serum IgE levels were measured in the study group, probably due to concurrent intestinal helminthiasis. A low proportion of the group also had detectable levels of specific anti-Leishmania IgE antibody. Total and specific IgE levels were also sex dependent (lowest in females), and an inverse correlation was found between these levels and DTH responsiveness, possibly reflecting the intervention of regulatory influences of T-lymphocyte activity.

Entities: Disease Gene

Mesh：

Substances：
Immunoglobulin E

Year: 1982 PMID： 7152676 PMCID： PMC347830 DOI： 10.1128/iai.38.3.877-881.1982

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

21 in total

1. Comparison of intradermal and serologic tests for the diagnosis of amebiasis.

Authors: S E Maddison; I G Kagan; R Elsdon-Dew
Journal: Am J Trop Med Hyg Date: 1968-07 Impact factor: 2.345

2. Immunity in cutaneous leishmaniasis of the guinea-pig.

Authors: A D Bryceson; R S Bray; R A Wolstencroft; D C Dumonde
Journal: Clin Exp Immunol Date: 1970-09 Impact factor: 4.330

3. Immunoglobulin levels in Ethiopian preschool children with special reference to high concentrations of immunoglobulin E (IgND).

Authors: S G Johansson; T Mellbin; B Vahlquist
Journal: Lancet Date: 1968-05-25 Impact factor: 79.321

4. A new and simple radioimmunoassay method for the determination of IgE.

Authors: M Ceska; U Lundkvist
Journal: Immunochemistry Date: 1972-10

5. Potentiated reagin response to egg albumin and conalbumin in Nippostrongylus brasiliensis infected rats.

Authors: T S Orr; A M Blair
Journal: Life Sci Date: 1969-10-15 Impact factor: 5.037

6. Influence of IgG antibody and glycopeptide allergens on the correlation between the radioallergosorbent test (RAST) and skin testing or bronchial challenge with alternaria.

Authors: N R Lynch; P Dunand; R W Newcomb; H Chai; J Bigley
Journal: Clin Exp Immunol Date: 1975-10 Impact factor: 4.330

4. Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana.

Authors: A Satoskar; J Alexander
Journal: Immunology Date: 1995-01 Impact factor: 7.397

5. BALB/c mice deficient in CD4 T cell IL-4Rα expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

Authors: Karen J Bryson; Owain R Millington; Thabang Mokgethi; H Adrienne McGachy; Frank Brombacher; James Alexander
Journal: PLoS Negl Trop Dis Date: 2011-01-04

6. Cerebrospinal Nematodiasis in 20 Camelids.

Authors: F R Bertin; S D Taylor
Journal: J Vet Intern Med Date: 2016-05-07 Impact factor: 3.333

6 in total

Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis.

1. Comparison of intradermal and serologic tests for the diagnosis of amebiasis.

2. Immunity in cutaneous leishmaniasis of the guinea-pig.

3. Immunoglobulin levels in Ethiopian preschool children with special reference to high concentrations of immunoglobulin E (IgND).

4. A new and simple radioimmunoassay method for the determination of IgE.

5. Potentiated reagin response to egg albumin and conalbumin in Nippostrongylus brasiliensis infected rats.

6. Influence of IgG antibody and glycopeptide allergens on the correlation between the radioallergosorbent test (RAST) and skin testing or bronchial challenge with alternaria.

7. The effects of sex and age on serum IgE concentrations in three ethnic groups.

8. Application of in vitro and in vivo assay techniques in the isolation of rye grass (Lolium perenne) pollen allergens.

9. Numerical immunotaxonomy of Leishmania. I. Differentiation of four strains of Leishmania by serological tests.

10. Immunology of leishmaniasis.

Review 1. Sex-associated hormones and immunity to protozoan parasites.

2. Leishmania immunoassay: IgE antibody to culture medium components.

3. Cutaneous leishmaniasis: immune complex formation and necrosis in the acute phase.

4. Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana.

5. BALB/c mice deficient in CD4 T cell IL-4Rα expression control Leishmania mexicana Load although female but not male mice develop a healer phenotype.

6. Cerebrospinal Nematodiasis in 20 Camelids.