Literature DB >> 7150254

Regulation of 3-hydroxybutyrate formation and secretion of very-low-density-lipoprotein triacylglycerol by perfused livers from fed and starved rats.

M E Laker, P A Mayes.   

Abstract

Acetoacetate was the sole ketone body formed when livers from starved rats were perfused with minimal concentrations of non-esterified fatty acid. Absence of 3-hydroxybutyrate was related to a low substrate potential, which caused a more oxidized redox state and a decreased [ATP]/[ADP] ratio. Only under conditions of comparable non-esterified fatty acid uptake was lipoprotein triacylglycerol production inversely related to ketogenesis.

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Year:  1982        PMID： 7150254      PMCID： PMC1158602          DOI： 10.1042/bj2060427

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  11 in total

1.  Fatty acid and 3- -hydroxysterol synthesis in the perfused rat liver. Including measurements on the production of lactate, pyruvate, -hydroxy-butyrate, and acetoacetate by the fed liver.

Authors:  H Brunengraber; M Boutry; J M Lowenstein
Journal:  J Biol Chem       Date:  1973-04-25       Impact factor: 5.157

2.  Metabolism of free fatty acids in isolated liver cells. Factors affecting the partition between esterification and oxidation.

Authors:  J A Ontko
Journal:  J Biol Chem       Date:  1972-03-25       Impact factor: 5.157

3.  Control mechanisms of gluconeogenesis and ketogenesis. II. Interactions between fatty acid oxidation and the citric acid cycle in perfused rat liver.

Authors:  J R Williamson; R Scholz; E T Browning
Journal:  J Biol Chem       Date:  1969-09-10       Impact factor: 5.157

4.  Regulation of ketogenesis in the liver.

Authors:  P A Mayes; M E Laker
Journal:  Biochem Soc Trans       Date:  1981-08       Impact factor: 5.407

5.  The immediate and long term effects of clofibrate on the metabolism of the perfused rat liver.

Authors:  M E Laker; P A Mayes
Journal:  Biochem Pharmacol       Date:  1979-09-15       Impact factor: 5.858

6.  On the maximal possible rate of ketogenesis.

Authors:  J P Flatt
Journal:  Diabetes       Date:  1972-01       Impact factor: 9.461

7.  The relationship between the rates of conversion of palmitate into citrate or acetoacetate and the acetyl-coenzyme A content of rat-liver mitochondria.

Authors:  D Shepherd; D W Yates; P B Garland
Journal:  Biochem J       Date:  1965-12       Impact factor: 3.857

8.  Regulation of fat metabolism of the liver.

Authors:  P A Mayes; J M Felts
Journal:  Nature       Date:  1967-08-12       Impact factor: 49.962

9.  Increased secretion of very low density lipoprotein triglyceride following inhibition of long chain fatty acid oxidation in isolated rat liver.

Authors:  T Ide; J A Ontko
Journal:  J Biol Chem       Date:  1981-10-25       Impact factor: 5.157

10.  Effect of hyperthyroidism and hypothyroidism on lipid and carbohydrate metabolism of the perfused rat liver.

Authors:  M E Laker; P A Mayes
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857
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  3 in total

1.  Peroxisomal beta-oxidation from endogenous substrates. Demonstration through H2O2 production in the unanaesthetized mouse.

Authors:  C Van den Branden; I Kerckaert; F Roels
Journal:  Biochem J       Date:  1984-03-15       Impact factor: 3.857

2.  Effect of ethanol on lipid metabolism in cultured hepatocytes.

Authors:  N Grunnet; J Kondrup; J Dich
Journal:  Biochem J       Date:  1985-06-15       Impact factor: 3.857

Review 3.  Exercise and dietary-mediated reductions in postprandial lipemia.

Authors:  Eric P Plaisance; Gordon Fisher
Journal:  J Nutr Metab       Date:  2014-06-29
  3 in total

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