| Literature DB >> 7148505 |
Abstract
The use of oral contraceptives (OC) and smoking habits were studied by using a questionnaire in a random population sample of women from two counties of Eastern Finland in 1972. The participation rate was 95%. Data on use of OC and smoking were collected for 2,653 women aged 35-49 years. During the next seven years, 27 of them had developed an acute myocardial infarction (AMI). Smokers had a 2.6-fold (95% confidence interval (CI)=1.2-6.0) crude risk of developing AMI compared with non-smokers. Women taking OC had a 1.3-fold (95% CI = 0.4-6.9) risk of developing AMI compared with those who did not. Women who both smoked and used OC had a 7.2-fold (95% CI = 2.1-24.7) risk of AMI compared with non-smokers and non-users of OC. The results indicate that use of OC is associated with an excessive risk of AMI among female smokers.Entities:
Keywords: Age Factors; Behavior; Biology; Cardiovascular Effects; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Methods--side effects; Demographic Factors; Developed Countries; Diseases; Europe; Family Planning; Finland; Heart Diseases; High Risk Women; Northern Europe; Oral Contraceptives--side effects; Physiology; Population; Population Characteristics; Prospective Studies; Reproduction; Research Methodology; Scandinavia; Smoking; Studies
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Year: 1982 PMID： 7148505 DOI： 10.1111/j.0954-6820.1982.tb03186.x
Source DB: PubMed Journal: Acta Med Scand ISSN： 0001-6101