| Literature DB >> 7145463 |
Abstract
Homogenates of Trypanosoma congolense and particulate and supernatant fractions thereof were, by two different techniques, shown to activate bovine complement via the alternative pathway. (1) All three preparations converted complement factor Bbov to its split product B gamma 2 as demonstrated (a) qualitatively by immunoelectrophoresis and (b) quantitatively by radial immunodiffusion. (2) Lysis of guinea-pig erythrocytes by bovine complement via the alternative pathway was inhibited by whole homogenates and particulate fractions of T. congolense organisms.Entities:
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Year: 1982 PMID: 7145463 DOI: 10.1111/j.1365-3024.1982.tb00444.x
Source DB: PubMed Journal: Parasite Immunol ISSN: 0141-9838 Impact factor: 2.280