Literature DB >> 7145023

Serotonin receptor modulation by estrogen in discrete brain nuclei.

A Biegon, C T Fischette, T C Rainbow, B S McEwen.   

Abstract

The effect of estradiol on serotonin (5HT1) receptors of ovariectomized female rats was studied in discrete brain nuclei by a micro-binding assay and quantitative autoradiography. The two methods show similar distribution of the 5HT1 receptor and estradiol significantly increases the density of receptors in the preoptic area, anterior hypothalamus, lateral septum and arcuate-median eminence. The increase in 5HT1 receptors in these particular nuclei may be related to estrogen control of ovulation and/or other estrogen-mediated central phenomena.

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Year:  1982        PMID： 7145023     DOI： 10.1159/000123396

Source DB:  PubMed          Journal:  Neuroendocrinology        ISSN： 0028-3835            Impact factor:   4.914


  6 in total

1.  Rat brain monoamine and Serotonin S2 receptor changes during pregnancy.

Authors:  J Glaser; V A Russell; A S de Villiers; J A Searson; J J Taljaard
Journal:  Neurochem Res       Date:  1990-10       Impact factor: 3.996

Review 2.  Ovarian hormone fluctuation, neurosteroids, and HPA axis dysregulation in perimenopausal depression: a novel heuristic model.

Authors:  Jennifer L Gordon; Susan S Girdler; Samantha E Meltzer-Brody; Catherine S Stika; Rebecca C Thurston; Crystal T Clark; Beth A Prairie; Eydie Moses-Kolko; Hadine Joffe; Katherine L Wisner
Journal:  Am J Psychiatry       Date:  2015-01-13       Impact factor: 18.112

Review 3.  The role of central serotonergic dysfunction in the aetiology of premenstrual dysphoric disorder: therapeutic implications.

Authors:  B L Parry
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

Review 4.  Ovarian steroids and serotonin neural function.

Authors:  C L Bethea; M Pecins-Thompson; W E Schutzer; C Gundlah; Z N Lu
Journal:  Mol Neurobiol       Date:  1998-10       Impact factor: 5.590

5.  Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides.

Authors:  Maura Boldrini; Mark D Underwood; J John Mann; Victoria Arango
Journal:  J Psychiatr Res       Date:  2007-06-15       Impact factor: 4.791

6.  Estrogen alters behavior and forebrain c-fos expression in ovariectomized rats subjected to the forced swim test.

Authors:  I M Rachman; J R Unnerstall; D W Pfaff; R S Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1998-11-10       Impact factor: 11.205
  6 in total

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