Literature DB >> 7142961

Determination of methylenomycin A synthesis by the pSV1 plasmid from Streptomyces violaceus-ruber SANK 95570.

A Aguilar, D A Hopwood.   

Abstract

A plasmid (pSV1) of 110 x 10(6) daltons from a methylenomycin A producing strain of Streptomyces violaceus-ruber was detected on an isolated from agarose gels. Elimination of this plasmid by protoplasting and regeneration resulted in the simultaneous loss of methylenomycin A production and resistance. pSV1 hybridized with pBR322 containing a cloned fragment of 1.7 x 10(6) daltons from S. coelicolor A3(2) which codes for methylenomycin A resistance. The pSV1 plasmid could be transferred to S. lividans by conjugation and by transformation and plasmid DNA identical in size to pSV1 could be isolated from the recipient strains. These experiments show that pSV1 codes for methylenomycin A production and resistance, in close analogy to the SCP1 plasmid from S. coelicolor A3(2).

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Year:  1982        PMID： 7142961     DOI： 10.1099/00221287-128-8-1893

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  9 in total

1.  Cyclization of a cellular dipentaenone by Streptomyces coelicolor cytochrome P450 154A1 without oxidation/reduction.

Authors:  Qian Cheng; David C Lamb; Steven L Kelly; Li Lei; F Peter Guengerich
Journal:  J Am Chem Soc       Date:  2010-11-03       Impact factor: 15.419

2.  Physical characterization of SCP1, a giant linear plasmid from Streptomyces coelicolor.

Authors:  H Kinashi; M Shimaji-Murayama
Journal:  J Bacteriol       Date:  1991-02       Impact factor: 3.490

Review 3.  The TetR family of regulators.

Authors:  Leslie Cuthbertson; Justin R Nodwell
Journal:  Microbiol Mol Biol Rev       Date:  2013-09       Impact factor: 11.056

4.  Characterization of the replication, transfer, and plasmid/lytic phage cycle of the Streptomyces plasmid-phage pZL12.

Authors:  Li Zhong; Qiuxiang Cheng; Xinli Tian; Liqian Zhao; Zhongjun Qin
Journal:  J Bacteriol       Date:  2010-05-14       Impact factor: 3.490

5.  Cloning and physical mapping of the EcoRI fragments of the giant linear plasmid SCP1.

Authors:  M Redenbach; K Ikeda; M Yamasaki; H Kinashi
Journal:  J Bacteriol       Date:  1998-05       Impact factor: 3.490

6.  Nucleotide sequence of afsB, a pleiotropic gene involved in secondary metabolism in Streptomyces coelicolor A3(2) and "Streptomyces lividans".

Authors:  S Horinouchi; H Suzuki; T Beppu
Journal:  J Bacteriol       Date:  1986-10       Impact factor: 3.490

7.  An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2).

Authors:  G Hobbs; A I Obanye; J Petty; J C Mason; E Barratt; D C Gardner; F Flett; C P Smith; P Broda; S G Oliver
Journal:  J Bacteriol       Date:  1992-03       Impact factor: 3.490

8.  High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae.

Authors:  J Stonesifer; P Matsushima; R H Baltz
Journal:  Mol Gen Genet       Date:  1986-03

9.  Resistance, regulatory and production genes for the antibiotic methylenomycin are clustered.

Authors:  K F Chater; C J Bruton
Journal:  EMBO J       Date:  1985-07       Impact factor: 11.598
  9 in total

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