Literature DB >> 7140862

Quercetin, flavonoids and the life-span of mice.

E Jones, R E Hughes.   

Abstract

A dietary supplement of 0.1% quercetin significantly reduced the life span of mice. The effect was predominantly on the 'shorter living' males. A blackcurrant juice extract, containing a mixture of flavonoids in addition to quercetin, prolonged significantly the life span of the 'older dying' females. The significance of these results vis-a-vis aging mechanisms and the dietary intake of quercetin is discussed.

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Year:  1982        PMID: 7140862     DOI: 10.1016/0531-5565(82)90027-4

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN: 0531-5565            Impact factor:   4.032


  8 in total

Review 1.  Regulation of SIRT1 in cellular functions: role of polyphenols.

Authors:  Sangwoon Chung; Hongwei Yao; Samuel Caito; Jae-Woong Hwang; Gnanapragasam Arunachalam; Irfan Rahman
Journal:  Arch Biochem Biophys       Date:  2010-05-05       Impact factor: 4.013

2.  Ameliorating effect of quercetin on acute pentylenetetrazole induced seizures in rats.

Authors:  Fatih Sefil; Ibrahim Kahraman; Recep Dokuyucu; Hasan Gokce; Atakan Ozturk; Okan Tutuk; Mehmet Aydin; Umit Ozkan; Neslihan Pinar
Journal:  Int J Clin Exp Med       Date:  2014-09-15

3.  Quercetin enhances tumorigenicity induced by N-ethyl-N'-nitro-N-nitrosoguanidine in the duodenum of mice.

Authors:  Yoshizumi Matsukawa; Hoyoku Nishino; Mitsunori Yoshida; Hiroyuki Sugihara; Kanade Katsura; Tetsurou Takamatsu; Junichi Okuzumi; Katsuhiko Matsumoto; Fumiko Sato-Nishimori; Toshiyuki Sakai
Journal:  Environ Health Prev Med       Date:  2002-01       Impact factor: 3.674

4.  Effects of Grape Skin Extract on Age-Related Mitochondrial Dysfunction, Memory and Life Span in C57BL/6J Mice.

Authors:  Heike Asseburg; Carmina Schäfer; Madeleine Müller; Stephanie Hagl; Maximilian Pohland; Dirk Berressem; Marta Borchiellini; Christina Plank; Gunter P Eckert
Journal:  Neuromolecular Med       Date:  2016-07-25       Impact factor: 3.843

5.  Potential mutagenic activity of some vitamin preparations in the human gut.

Authors:  J A Mader; I A Macdonald
Journal:  Appl Environ Microbiol       Date:  1984-10       Impact factor: 4.792

6.  Geroprotective and Radioprotective Activity of Quercetin, (-)-Epicatechin, and Ibuprofen in Drosophila melanogaster.

Authors:  Ekaterina Proshkina; Ekaterina Lashmanova; Eugenia Dobrovolskaya; Nadezhda Zemskaya; Anna Kudryavtseva; Mikhail Shaposhnikov; Alexey Moskalev
Journal:  Front Pharmacol       Date:  2016-12-23       Impact factor: 5.810

Review 7.  The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc.

Authors:  Imre Hegedüs; Kitti Andreidesz; József L Szentpéteri; Zoltán Kaleta; László Szabó; Krisztián Szigeti; Balázs Gulyás; Parasuraman Padmanabhan; Ferenc Budan; Domokos Máthé
Journal:  Int J Mol Sci       Date:  2022-09-22       Impact factor: 6.208

8.  The Evaluation of Geroprotective Effects of Selected Flavonoids in Drosophila melanogaster and Caenorhabditis elegans.

Authors:  Ekaterina Lashmanova; Nadezhda Zemskaya; Ekaterina Proshkina; Anna Kudryavtseva; Marina Volosnikova; Elena Marusich; Sergey Leonov; Alex Zhavoronkov; Alexey Moskalev
Journal:  Front Pharmacol       Date:  2017-12-07       Impact factor: 5.810

  8 in total

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