Literature DB >> 7140697

Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.

S V Kevy, M S Jacobson.   

Abstract

The effects of di(2-ethylhexyl) phthalate (DEHP) on hepatic function and histology were evaluated in the rhesus monkey undergoing platelet and plasma transfusion. The average cumulative amount infused in one year is comparable to that received by patients who undergo chronic transfusion. Abnormalities in hepatic scan and BSP kinetics persisted for up to 26 months after transfusion, as did histologic abnormalities. Patients undergoing maintenance hemodialysis receive a yearly dose of DEHP which is 10-20 times that which produced hepatotoxicity in the transfused rhesus.

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Year:  1982        PMID： 7140697      PMCID： PMC1569017          DOI： 10.1289/ehp.824557

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN： 0091-6765            Impact factor:   9.031


  8 in total

1.  Identification and measurement of plasticizer in neonatal tissues after umbilical catheters and blood products.

Authors:  L S Hillman; S L Goodwin; W R Sherman
Journal:  N Engl J Med       Date:  1975-02-20       Impact factor: 91.245

2.  Significance of alterations in extraction and distribution of colloidal chromic phosphate in patients with liver disease.

Authors:  J G RANKIN; M R PLAYOUST; R W BEAL
Journal:  J Lab Clin Med       Date:  1961-12

3.  The toxicity of human serum stored in flexible polyvinylchloride containers on human fibroblast cell cultures: an effect of di-2-ethylhexyl phthalate.

Authors:  M S Jacobson; R Parkman; L N Button; R J Jaeger; S V Kevy
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1974-10

4.  The absorption, metabolism and tissue distribution of di(2-ethylhexyl)phthalate in rats.

Authors:  J W Daniel; H Bratt
Journal:  Toxicology       Date:  1974-03       Impact factor: 4.221

5.  Migration of a phthalate ester plasticizer from polyvinyl chloride blood bags into stored human blood and its localization in human tissues.

Authors:  R J Jaeger; R J Rubin
Journal:  N Engl J Med       Date:  1972-11-30       Impact factor: 91.245

6.  Compartmental analysis of sulfobromophthalein transport in normal patients and patients with hepatic dysfunction.

Authors:  S H Quarfordt; H L Hilderman; D Valle; E Waddell
Journal:  Gastroenterology       Date:  1971-02       Impact factor: 22.682

7.  Identification of the metabolites of di-(2-ethylhexyl) phthalate in urine from the African green monkey.

Authors:  P W Albro; J R Hass; C C Peck; D G Odam; J T Corbett; F J Bailey; H E Blatt; B B Barrett
Journal:  Drug Metab Dispos       Date:  1981 May-Jun       Impact factor: 3.922

8.  Effects of a plasticizer leached from polyvinyl chloride on the subhuman primate: a consequence of chronic transfusion therapy.

Authors:  M S Jacobson; S V Kevy; R J Grand
Journal:  J Lab Clin Med       Date:  1977-05
  8 in total
  7 in total

Review 1.  PVC as pharmaceutical packaging material. A literature survey with special emphasis on plasticized PVC bags.

Authors:  A A Van Dooren
Journal:  Pharm Weekbl Sci       Date:  1991-06-21

2.  Plasticized polyvinylchloride as a temporary dressing for burns.

Authors:  G Wilson; G French
Journal:  Br Med J (Clin Res Ed)       Date:  1987-02-28

3.  Ovarian Metabolism of an Environmentally Relevant Phthalate Mixture.

Authors:  Genoa R Warner; Zhong Li; Madeline L Houde; Cassandra E Atkinson; Daryl D Meling; Catheryne Chiang; Jodi A Flaws
Journal:  Toxicol Sci       Date:  2019-05-01       Impact factor: 4.849

4.  Significant changes in follicular fluid phthalate metabolite levels reflect the lifestyle changes brought about by the strict COVID-19 lockdown in India.

Authors:  Firuza Rajesh Parikh; Shonali Uttamchandani; Nandkishor Naik; Madhavi Panpalia; Mangesh Sanap; Dhananjaya Kulkarni; Prachi Sinkar; Pratiksha Khandare; Prashant Makwana; Smita Gawas; Anahita Pandole; Rajesh Parikh
Journal:  F S Sci       Date:  2022-06-09

5.  Plasticizer extraction of Taxol infusion solution from various infusion devices.

Authors:  B Mass; C Huber; I Krämer
Journal:  Pharm World Sci       Date:  1996-04

6.  Effects of the plasticiser DEHP on lung of newborn rats: catalase immunocytochemistry and morphometric analysis.

Authors:  Roberta Magliozzi; Roberta Nardacci; Gianfranco Scarsella; Valeria Di Carlo; Stefania Stefanini
Journal:  Histochem Cell Biol       Date:  2003-06-11       Impact factor: 4.304

7.  Follow-up study of adolescents exposed to di(2-ethylhexyl) phthalate (DEHP) as neonates on extracorporeal membrane oxygenation (ECMO) support.

Authors:  Khodayar Rais-Bahrami; Susan Nunez; Mary E Revenis; Naomi L C Luban; Billie L Short
Journal:  Environ Health Perspect       Date:  2004-09       Impact factor: 9.031
  7 in total

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