Literature DB >> 7140488

Lymphatic role in the pathogenesis of fat malabsorption in liver cirrhosis in rats.

S Miura, H Asakura, Y Munakata, K Kobayashi, M Yoshioka, T Morishita, M Tsuchiya.   

Abstract

Intestinal fat absorption was examined in rats with CCl4-induced liver cirrhosis. Marked lymphangiectasia of the small intestine was observed in rats after CCl4 was given subcutaneously biweekly for 10--12 weeks. Intestinal epithelial uptake of linoleic acid administered in the loop was not impaired, but accumulation of lipid droplets in the intestinal epithelial cells and disturbed lymphatic transport of absorbed fat were observed in these rats. These data suggest that lymphostasis of the intestine may play an important role in fat malabsorption in liver cirrhosis.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7140488     DOI： 10.1007/bf01391751

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  18 in total

1.  SYSTEMIC LYMPHATIC ABNORMALITIES ASSOCIATED WITH GASTROINTESTINAL PROTEIN LOSS SECONDARY TO INTESTINAL LYMPHANGIECTASIA.

Authors:  M POMERANTZ; T A WALDMANN
Journal:  Gastroenterology       Date:  1963-12       Impact factor: 22.682

2.  THE INTESTINAL ABSORPTION AND METABOLISM OF MICELLAR SOLUTIONS OF LIPIDS.

Authors:  J M JOHNSTON; B BORGSTROEM
Journal:  Biochim Biophys Acta       Date:  1964-08-05

3.  Smal bowel absorption in portal cirrhosis with ascites.

Authors:  A I FRIEDMAN; G McEWAN
Journal:  Am J Gastroenterol       Date:  1963-02       Impact factor: 10.864

4.  Peroral biopsy of the intestinal mucosa in hepatic cirrhosis.

Authors:  G ASTALDI; E STROSSELLI
Journal:  Am J Dig Dis       Date:  1960-07

5.  Clinical Studies on Behçet's Syndrome.

Authors:  Y Oshima; T Shimizu; R Yokohari; T Matsumoto; K Kano; T Kagami; H Nagaya
Journal:  Ann Rheum Dis       Date:  1963-01       Impact factor: 19.103

Review 6.  Malabsorption in cirrhosis.

Authors:  W G Linscheer
Journal:  Am J Clin Nutr       Date:  1970-04       Impact factor: 7.045

7.  Histopathological and electron microscopic studies of lymphangiectasia of the small intestine in Behçet's disease.

Authors:  H Asakura; A Morita; T Morishita; M Tsuchiya; Y Watanabe; Y Enomoto
Journal:  Gut       Date:  1973-03       Impact factor: 23.059

8.  Modification of chronic carbon tetrachloride hepatic injury by N,N'-diphenyl-p-phenylenediamine.

Authors:  A D Hartman; N R Di Luzio; M L Trumbull
Journal:  Exp Mol Pathol       Date:  1968-12       Impact factor: 3.362

9.  Reversible protein-losing enteropathy with intestinal lymphangiectasia secondary to chronic constrictive pericarditis.

Authors:  P Wilkinson; B Pinto; J R Senior
Journal:  N Engl J Med       Date:  1965-11-25       Impact factor: 91.245

10.  Endoscopic and histopathological study on primary and secondary intestinal lymphangiectasia.

Authors:  H Asakura; S Miura; T Morishita; S Aiso; T Tanaka; T Kitahora; M Tsuchiya; Y Enomoto; Y Watanabe
Journal:  Dig Dis Sci       Date:  1981-04       Impact factor: 3.199
View more
  2 in total

1.  Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat.

Authors:  J Kountouras; B H Billing; P J Scheuer
Journal:  Br J Exp Pathol       Date:  1984-06

Review 2.  The Sea Lamprey as an Etiological Model for Biliary Atresia.

Authors:  Yu-Wen Chung-Davidson; Chu-Yin Yeh; Weiming Li
Journal:  Biomed Res Int       Date:  2015-05-26       Impact factor: 3.411
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.