| Literature DB >> 7139948 |
A Shulkes, P Chick, H Wong, J H Walsh.
Abstract
A specific radioimmunoassay for neurotensin in plasma has been developed with a sensitivity of 2 pmol/l of plasma. The antiserum was directed towards the amino terminal region of neurotensin and did not cross-react with other gastrointestinal peptides. Non-specific interference was eliminated and the sensitivity increased by extracting the plasma samples with ethanol prior to assay. Within- and between-assay coefficients of variation were 7.8% and .12% respectively. The mean plasma concentration of neurotensin in 30 fasting subjects was 29 +/- 4 pmol/l. A mixed meal increased plasma neurotensin from 16 +/- 2 to 53 +/- 6 pmol/l at 2 h.Entities:
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Year: 1982 PMID： 7139948 DOI： 10.1016/0009-8981(82)90044-4
Source DB: PubMed Journal: Clin Chim Acta ISSN： 0009-8981 Impact factor: 3.786