Literature DB >> 7138749

A method for monitoring drug effects on male sexual response: the effect of single dose labetalol.

A J Riley, E J Riley, H J Davies.   

Abstract

1 A method for monitoring the effect of drugs on the genital response to stimulation provided by vibration is described. 2 Using this method, the effect on male sexual response of two oral doses (100 mg and 300 mg) labetalol were studied and compared with placebo in six subjects. 3 Labetalol did not affect the attainment or maintenance of erection. 4 Labetalol delayed ejaculation in a dose-related manner. 5 Labetalol treatment resulted in a significant dose-related delay in detumescence.

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Year:  1982        PMID： 7138749      PMCID： PMC1427492          DOI： 10.1111/j.1365-2125.1982.tb04959.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  15 in total

1.  CYCLE OF PENILE ERECTION SYNCHRONOUS WITH DREAMING (REM) SLEEP. PRELIMINARY REPORT.

Authors:  C FISHER; J GORSS; J ZUCH
Journal:  Arch Gen Psychiatry       Date:  1965-01

2.  Some physiological and pharmacological characteristics of the motor transmission in the guinea-pig vas deferens.

Authors:  N Ambache; M A Zar
Journal:  J Physiol       Date:  1971-01       Impact factor: 5.182

3.  Failure of ejaculation with indoramin.

Authors:  B Pentland; D A Anderson; J A Critchley
Journal:  Br Med J (Clin Res Ed)       Date:  1981-05-02

4.  The role of central adrenergic receptors in the reflex release of oxytocin.

Authors:  E Tribollet; G Clarke; J J Dreifuss; D W Lincoln
Journal:  Brain Res       Date:  1978-02-17       Impact factor: 3.252

5.  Sleep erection monitoring in the evaluation of male erectile failure.

Authors:  J G Bohlen
Journal:  Urol Clin North Am       Date:  1981-02       Impact factor: 2.241

6.  Observations on the effect of labetalol on pregnancy and parturition in normotensive rats.

Authors:  E T Whalley
Journal:  Gen Pharmacol       Date:  1980

7.  Plasma noradrenaline and dopamine-beta-hydroxylase during human sexual activity.

Authors:  C Wiedeking; M G Ziegler; C R Lake
Journal:  J Psychiatr Res       Date:  1979       Impact factor: 4.791

8.  A simple transducer for measuring penile erection with comments on its use in the treatment of sexual disorders.

Authors:  J H Bancroft; H G Jones; B R Pullan
Journal:  Behav Res Ther       Date:  1966-08

9.  The effect of labetalol and propranolol on the pressor response to sexual arousal in women.

Authors:  A J Riley; E J Riley
Journal:  Br J Clin Pharmacol       Date:  1981-09       Impact factor: 4.335

10.  Increase in oxytocin secretion at ejaculation in male.

Authors:  S Ogawa; S Kudo; Y Kitsunai; S Fukuchi
Journal:  Clin Endocrinol (Oxf)       Date:  1980-07       Impact factor: 3.478
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  1 in total

Review 1.  Combined alpha- and beta-receptor inhibition in the treatment of hypertension.

Authors:  B N Prichard
Journal:  Drugs       Date:  1984       Impact factor: 9.546
  1 in total

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