| Literature DB >> 7132574 |
J E Morley, A S Levine, S E Silvis.
Abstract
Parenteral administration of the opiate antagonist, naltrexone, had a cytoprotective effect against stress-induced ulceration. This effect appears to be due to blockade of peripheral rather than central endogenous opiates and is not related to the central inhibitory effect of opiates on gastric acid secretion. Opiates have complex effects on gastric mucosal blood flow which may explain their role in stress ulceration.Entities:
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Year: 1982 PMID： 7132574 DOI： 10.1016/0024-3205(82)90771-8
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037