A clinical study of econazole cream in the treatment of fungal skin infections.

An open assessment of the efficacy of econazole nitrate (Pevaryl) cream in the treatment of 140 patients with proven dermatomycoses was conducted at five university health centres. Specimens were obtained from 129 patients at the end of treatment and 121 (93.8 per cent) showed no evidence of fungi. After a further month without treatment 108 patients reattended and, of these, 98 (90.9 per cent) remained clinically and mycologically free from infection. Trichophyton rubrum and Epidermophyton floccosum were the fungi most frequently isolated, and the distribution of species and areas of the body affected were similar for all five centres.