Literature DB >> 7131280

Development of a method for study of the tendency of drug products to adhere to the esophagus.

M Marvola, K Vahervuo, A Sothmann, E Marttila, M Rajaniemi.   

Abstract

A method to determine the adherence of drugs to the esophagus was developed using isolated swine esophagi. A number of types of tablets and capsules (e.g., of doxycycline) were tested. The results showed that the tendency of products to adhere to the esophagus can be regulated by pharmaceutical properties. It was concluded that the method described is simple, inexpensive, and accurate.

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Year:  1982        PMID: 7131280     DOI: 10.1002/jps.2600710904

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  5 in total

Review 1.  Bioadhesive dosage forms for esophageal drug delivery.

Authors:  Hannah Batchelor
Journal:  Pharm Res       Date:  2005-02       Impact factor: 4.200

Review 2.  From sticky stuff to sweet receptors--achievements, limits and novel approaches to bioadhesion.

Authors:  C M Lehr
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1996 Apr-Jun       Impact factor: 2.441

3.  Sticking of dosage forms in the gastrointestinal tract.

Authors:  C G Wilson; J G Hardy; S S Davis
Journal:  Gut       Date:  1986-02       Impact factor: 23.059

4.  Changing the enzalutamide form from a capsule to a tablet improves the adherence of medicine intake: A case of a significant decrease in the prostate-specific antigen level and improvement in radiographic findings.

Authors:  Takashi Kawahara; Sahoko Ninomiya; Yasuhide Miyoshi; Masahiro Yao; Hiroji Uemura
Journal:  IJU Case Rep       Date:  2019-03-18

5.  Barrier effect of Esoxx(®) on esophageal mucosal damage: experimental study on ex-vivo swine model.

Authors:  Massimo P Di Simone; Fabio Baldi; Valentina Vasina; Fabrizio Scorrano; Maria Laura Bacci; Antonella Ferrieri; Gilberto Poggioli
Journal:  Clin Exp Gastroenterol       Date:  2012-06-11
  5 in total

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