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Literature DB >> 7130979

Comparison of some peptidic and proteic ovine pineal fractions with a bovine pineal E5 fraction.

H P Noteborn, I Ebels, P Pévet, A C Reinharz, C Neacşu, C A Salemink.

Abstract

Using rather simple and mild extraction and separation methods, three ovine pineal fractions (XM 300 R-PP7.2' and PP7.2 S) were obtained, which contain peptidic/proteic substances and which show fluorescence characteristics of indoles. The ovine fractions were compared with the bovine pineal E-5 fraction. The ovine fractions are chemically sensitive to normal laboratory light and stable in red light (lambda greater than 600 nm). Immunologically, these fractions and the bovine E 5 fraction are stable. From the results of radioimmunological experiments it was concluded that the bovine pineal E 5 fraction as well as the ovine pineal fraction XM 300 R-PP7.2 and PP7.2S may contain (a) peptide(s) ending by the same carboxy terminal tripeptide Pro-Arg-Gly(NH2).

Entities: Chemical Species

Mesh：

Substances：

Year: 1982 PMID： 7130979 DOI： 10.1007/bf01243339

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

32 in total

1. Estimation of molecular weights of small proteins on polyacrylamide gel electrophoresis.

Authors: A Gonenne; J Lebowitz
Journal: Anal Biochem Date: 1975-04 Impact factor: 3.365

2. DISC ELECTROPHORESIS. I. BACKGROUND AND THEORY.

Authors: L ORNSTEIN
Journal: Ann N Y Acad Sci Date: 1964-12-28 Impact factor: 5.691

3. Separation of pineal extracts by gelfiltration. VI. Isolation and identification from sheep pineals of biopterin; comparison of the isolated compound with some synthetic pteridines and the biological activity in in vitro and in vivo bioassays.

Authors: M L van der Have-Kirchberg; A de Morée; J F van Laar; G J Gerwig; C Versluis; I Ebels
Journal: J Neural Transm Date: 1977 Impact factor: 3.575

7. Extraction of pineal and uterine tissue at different pH values: a preliminary report on the occurrence of a few groups of compounds in both tissues.

Authors: C J van der Horst; I Ebels
Journal: Cytobios Date: 1980

8. Decapeptide luteinizing hormone releasing hormone in ovine pineal gland.

Authors: J A King; R P Millar
Journal: J Endocrinol Date: 1981-12 Impact factor: 4.286

9. A survey of the location, isolation and identification of indoles, pteridines and some unknown active substances in sheep pineals. The possible significance of pteridines for the neuroendocrine control of neoplastic growth.

Authors: I Ebels
Journal: J Neural Transm Date: 1980 Impact factor: 3.575

10. Vasopressin- and oxytocin-containing fibres in the pineal gland and subcommissural organ of the rat.

Authors: R M Buijs; P Pévet
Journal: Cell Tissue Res Date: 1980 Impact factor: 5.249

1 in total

1. Partial purification of (a) low molecular weight ovine pineal compound(s) with an inhibiting effect on the growth of human melanoma cells in vitro.

Authors: H P Noteborn; H Bartsch; C Bartsch; D R Mans; J J Weusten; B Flehmig; I Ebels; C A Salemink
Journal: J Neural Transm Date: 1988 Impact factor: 3.575