Literature DB >> 7130421

Assessment of a radioisotopic assay for vitamin B12 using an intrinsic factor preparation with R proteins blocked by vitamin B12 analogues.

B Bain, G N Broom, J Woodside, R A Litwinczuk, S N Wickramasinghe.   

Abstract

A competitive protein binding radioassay kit for serum vitamin B(12) has been assessed. Precision, linearity, sensitivity, and specificity have been found to be satisfactory. Falsely-normal assay results in patients with vitamin B(12) deficiency have not been observed.

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Year:  1982        PMID： 7130421      PMCID： PMC497892          DOI： 10.1136/jcp.35.10.1110

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  11 in total

1.  Evidence that some patients with pernicious anemia are not recognized by radiodilution assay for cobalamin in serum.

Authors:  B A Cooper; V M Whitehead
Journal:  N Engl J Med       Date:  1978-10-12       Impact factor: 91.245

2.  A fault in the design of the deoxyuridine suppression test.

Authors:  S N Wickramasinghe; J E Saunders
Journal:  Clin Lab Haematol       Date:  1979

3.  The use of chicken serum for measurement of serum vitamin B12 concentration by radioisotope dilution: discription of method and comparison with microbiological assay results.

Authors:  R Green; P A Newmark; A M Musso; D L Mollin
Journal:  Br J Haematol       Date:  1974-07       Impact factor: 6.998

4.  Erroneously low results due to high nonspecific binding encountered with a radioassay kit that measures true serum vitamin B12.

Authors:  R J LeFebvre; A S Virji; B F Mertens
Journal:  Am J Clin Pathol       Date:  1980-08       Impact factor: 2.493

5.  Comparison of serum vitamin B12 estimation by saturation analysis with intrinsic factor and with R-protein as binding agents.

Authors:  R Zacharakis; M Muir; I Chanarin
Journal:  J Clin Pathol       Date:  1981-04       Impact factor: 3.411

6.  Cobalamin analogues are present in human plasma and can mask cobalamin deficiency because current radioisotope dilution assays are not specific for true cobalamin.

Authors:  J F Kolhouse; H Kondo; N C Allen; E Podell; R H Allen
Journal:  N Engl J Med       Date:  1978-10-12       Impact factor: 91.245

7.  Vitamin B12 quality control trials.

Authors:  D W Dawson; D I Fish; I D Frew; B Orton; T Roome
Journal:  Clin Lab Haematol       Date:  1981

8.  Forms of vitamin B12 in radioisotope dilution assays.

Authors:  J A Begley; C A Hall
Journal:  J Clin Pathol       Date:  1981-06       Impact factor: 3.411

9.  Use of an improved E. coli method for the measurement of cobalamin in serum: comparison with the E. gracilis assay results.

Authors:  N A Sourial
Journal:  J Clin Pathol       Date:  1981-04       Impact factor: 3.411

10.  Clinical significance of serum vitamin B12 measured by radioassay using pure intrinsic factor.

Authors:  I W Chen; E B Silberstein; H R Maxon; M Sperling; E Barnes
Journal:  J Nucl Med       Date:  1981-05       Impact factor: 10.057
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  3 in total

1.  Importance of low serum vitamin B12 and red cell folate concentrations in elderly hospital inpatients.

Authors:  E L Blundell; J H Matthews; S M Allen; A M Middleton; J E Morris; S N Wickramasinghe
Journal:  J Clin Pathol       Date:  1985-10       Impact factor: 3.411

2.  Correlations between holo-transcobalamin II, holo-haptocorrin, and total B12 in serum samples from healthy subjects and patients.

Authors:  S N Wickramasinghe; S Fida
Journal:  J Clin Pathol       Date:  1993-06       Impact factor: 3.411

3.  Assessment of the value of a competitive protein binding radioassay of folic acid in the detection of folic acid deficiency.

Authors:  B J Bain; S N Wickramasinghe; G N Broom; R A Litwinczuk; J Sims
Journal:  J Clin Pathol       Date:  1984-08       Impact factor: 3.411
  3 in total

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