Literature DB >> 7130338

Extreme insulin resistance in association with abnormally high binding affinity of insulin receptors from a patient with leprechaunism: evidence for a defect intrinsic to the receptor.

S I Taylor, J A Hedo, L H Underhill, M Kasuga, M J Elders, J Roth.   

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Year:  1982        PMID: 7130338     DOI: 10.1210/jcem-55-6-1108

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


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  14 in total

Review 1.  Insulin receptors and the clinician.

Authors:  R Taylor
Journal:  Br Med J (Clin Res Ed)       Date:  1986-04-05

2.  Fibroblasts from a leprechaun patient have defects in insulin binding and insulin receptor autophosphorylation.

Authors:  J A Maassen; M P Klinkhamer; G C van der Zon; H Sips; W Möller; H M Krans; D Lindhout; F A Beemer
Journal:  Diabetologia       Date:  1988-08       Impact factor: 10.122

3.  Two systems in vitro that show insulin-stimulated serine kinase activity towards the insulin receptor.

Authors:  D M Smith; M J King; G J Sale
Journal:  Biochem J       Date:  1988-03-01       Impact factor: 3.857

4.  Diabetes-induced functional and structural changes in insulin receptors from rat skeletal muscle.

Authors:  C F Burant; M K Treutelaar; M G Buse
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

5.  Binding specificity and intramolecular signal transmission of uncleaved insulin proreceptor in transformed lymphocytes from a patient with extreme insulin resistance.

Authors:  T Sasaoka; Y Shigeta; Y Takata; M Sugibayashi; A Hisatomi; M Kobayashi
Journal:  Diabetologia       Date:  1989-06       Impact factor: 10.122

6.  Tyrosine kinase activity of insulin receptors from an insulin-resistant patient with leprechaunism.

Authors:  A Cama; S I Taylor
Journal:  Diabetologia       Date:  1987-08       Impact factor: 10.122

7.  Insulin receptor degradation is accelerated in cultured lymphocytes from patients with genetic syndromes of extreme insulin resistance.

Authors:  A McElduff; J A Hedo; S I Taylor; J Roth; P Gorden
Journal:  J Clin Invest       Date:  1984-10       Impact factor: 14.808

8.  Defect in cooperativity in insulin receptors from a patient with a congenital form of extreme insulin resistance.

Authors:  S I Taylor; S Leventhal
Journal:  J Clin Invest       Date:  1983-06       Impact factor: 14.808

9.  Leprechaunism: an inherited defect in a high-affinity insulin receptor.

Authors:  L J Elsas; F Endo; E Strumlauf; J Elders; J H Priest
Journal:  Am J Hum Genet       Date:  1985-01       Impact factor: 11.025

10.  Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance.

Authors:  Salvatore Iovino; Alison M Burkart; Laura Warren; Mary Elizabeth Patti; C Ronald Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-01       Impact factor: 11.205

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