| Literature DB >> 7127250 |
Abstract
The glucose consumption rate of 9L rat brain tumor cells was determined as a function of concentration. Glucose uptake followed Michaelis-Menten kinetics with a Km of 0.58 mM and a Vmax of 1.6 pg/cell-min. The glucose diffusion coefficient in spheroids of 9L tumor cells was determined to be 1.5 x 10(-6) cm2/s at 37 degrees C. Using these parametric values, the glucose distribution in 9L multicell spheroids was calculated and related to the viable and necrotic zones.Entities:
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Year: 1982 PMID： 7127250 DOI： 10.1002/1097-0142(19821115)50:10<2066::aid-cncr2820501017>3.0.co;2-x
Source DB: PubMed Journal: Cancer ISSN： 0008-543X Impact factor: 6.860