Literature DB >> 7127179

Cerebral vascular responses to ketamine and thiopentone during foetal acidosis.

B G Pickering, R J Palahniuk, J Coté, J G Wade, M G Pash.   

Abstract

Using a chronic sheep preparation, with induced foetal acidosis, the effects of low and high dose thiopentone and ketamine on maternal and foetal cardiovascular dynamics were studied. Ketamine 4 mg . kg-1 and thiopentone 10 mg . kg-1 were both associated with marked reductions in foetal cerebral blood flow and cerebral oxygen delivery. Blood pressure and cerebral blood flow in the acidotic foetus was better preserved, however, following the lower dose of ketamine 2 mg . kg-1 than following thiopentone 6 mg . kg-1.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 7127179     DOI： 10.1007/bf03009409

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN： 0008-2856


  8 in total

1.  Nomograms and empirical equations relating oxygen tension, percentage saturation, and pH in maternal and fetal blood.

Authors:  A E HELLEGERS; J J SCHRUEFER
Journal:  Am J Obstet Gynecol       Date:  1961-02       Impact factor: 8.661

2.  Induction agents for Caesarean section. A comparison of thiopentone and ketamine.

Authors:  B Peltz; D M Sinclair
Journal:  Anaesthesia       Date:  1973-01       Impact factor: 6.955

3.  Two patterns of perinatal brain damage and their conditions of occurrence.

Authors:  R E Myers
Journal:  Am J Obstet Gynecol       Date:  1972-01-15       Impact factor: 8.661

4.  Anaesthetic induction of caesarean section with thiopentone, methohexitone and ketamine.

Authors:  P C Houlton; J W Downing; R J Buley; J G Brock-Utne
Journal:  S Afr Med J       Date:  1978-11-11

5.  Regional cerebral blood flow changes during severe fetal asphyxia produced by slow partial umbilical cord compression.

Authors:  G N Johnson; R J Palahniuk; W A Tweed; M V Jones; J G Wade
Journal:  Am J Obstet Gynecol       Date:  1979-09-01       Impact factor: 8.661

6.  Pressure passive cerebral blood flow and breakdown of the blood-brain barrier in experimental fetal asphyxia.

Authors:  H C Lou; N A Lassen; W A Tweed; G Johnson; M Jones; R J Palahniuk
Journal:  Acta Paediatr Scand       Date:  1979-01

7.  Impaired autoregulation of cerebral blood flow in the distressed newborn infant.

Authors:  H C Lou; N A Lassen; B Friis-Hansen
Journal:  J Pediatr       Date:  1979-01       Impact factor: 4.406

8.  Maternal halothane anesthesis reduces cerebral blood flow in the acidotic sheep fetus.

Authors:  R J Palahniuk; G A Doig; G N Johnson; M P Pash
Journal:  Anesth Analg       Date:  1980-01       Impact factor: 5.108
  8 in total
  2 in total

1.  Ketamine inhibits fetal ACTH responses to cerebral hypoperfusion.

Authors:  Melanie J Powers; Charles E Wood
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2006-12-07       Impact factor: 3.619

2.  The effect of ketamine anaesthesia on the acidotic fetal lamb.

Authors:  J Swartz; M Cumming; D Biehl
Journal:  Can J Anaesth       Date:  1987-05       Impact factor: 5.063
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.