Literature DB >> 7127056

Depression of natural killer cell activity by syphilitic serum and immune complexes.

J R Jensen, A S Jørgensen, K Thestrup-Pedersen.   

Abstract

Consecutive serum samples were obtained from patients with syphilis before and on three occasions after treatment. The sera contained immunosuppresive factors associated with the immunoglobulin fraction, which could depress the natural killer cell activity of healthy controls. There was no evidence that allogeneic or lymphocytotoxic antibodies played a role in immuno-suppression, which could be reproduced with both soluble and insoluble antigen-IgG-antibody complexes.

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Year:  1982        PMID： 7127056      PMCID： PMC1046078          DOI： 10.1136/sti.58.5.298

Source DB:  PubMed          Journal:  Br J Vener Dis        ISSN： 0007-134X


  14 in total

1.  Natural cytotoxic reactivity of human lymphocytes against a myeloid cell line: characterization of effector cells.

Authors:  W H West; G B Cannon; H D Kay; G D Bonnard; R B Herberman
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

2.  A functional comparison of human Fc-receptor-bearing lymphocytes active in natural cytotoxicity and antibody-dependent cellular cytotoxicity.

Authors:  H D Kay; G D Bonnard; W H West; R B Herberman
Journal:  J Immunol       Date:  1977-06       Impact factor: 5.422

3.  Reduced lymphocyte transformation due to a plasma factor in patients with active syphilis.

Authors:  G M Levene; J L Turk; D J Wright; A G Grimble
Journal:  Lancet       Date:  1969-08-02       Impact factor: 79.321

4.  Leucocyte migration and cell-mediated immunity in syphilis.

Authors:  K W Fulford; J Brostoff
Journal:  Br J Vener Dis       Date:  1972-12

5.  Circulating immune complexes in syphilis.

Authors:  J Sølling; K Sølling; K U Jakobsen; E From
Journal:  Acta Derm Venereol       Date:  1978       Impact factor: 4.437

6.  Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations.

Authors:  M Jondal; H Pross
Journal:  Int J Cancer       Date:  1975-04-15       Impact factor: 7.396

7.  Reactivity of lymphocytes from patients with syphilis towards T. pallidum antigen in the leucocyte migration and lymphocyte transformation tests.

Authors:  E From; K Thestrup-Pedersen; H Thulin
Journal:  Br J Vener Dis       Date:  1976-08

8.  In vitro cell response of Treponema pallidum-infected rabbits. II. Inhibition of lymphocyte response to phytohaemagglutinin by serum of T. pallidum-infected rabbits.

Authors:  V Wicher; K Wicher
Journal:  Clin Exp Immunol       Date:  1977-09       Impact factor: 4.330

9.  Selective phagocytic paralysis induced by immobilized immune complexes.

Authors:  M Rabinovitch; R E Manejias; V Nussenzweig
Journal:  J Exp Med       Date:  1975-10-01       Impact factor: 14.307

10.  Inhibition of lymphocyte mitogenesis by immobilized antigen-antibody complexes.

Authors:  J L Ryan; R D Arbeit; H B Dickler; P A Henkart
Journal:  J Exp Med       Date:  1975-10-01       Impact factor: 14.307
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  3 in total

1.  Immune studies in infants with congenital syphilis.

Authors:  G R Samson; D W Beatty; A F Malan
Journal:  Clin Exp Immunol       Date:  1990-08       Impact factor: 4.330

2.  Inhibition of human natural killer activity by antiserum against vitamin D-binding protein, a group-specific component (Gc).

Authors:  T Chujo; T Machii; S Tagawa; H Kuratsune; E Ueda; H Kimura; T Kitani
Journal:  Clin Exp Immunol       Date:  1989-05       Impact factor: 4.330

3.  Fluctuations in natural killer cell activity in early syphilis.

Authors:  J R Jensen; K Thestrup-Pedersen; E From
Journal:  Br J Vener Dis       Date:  1983-02
  3 in total

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