Literature DB >> 7126180

A study of the mechanism of quercetin oxygenation by 18O labelling. A comparison of the mechanism with that of haem degradation.

S B Brown, V Rajananda, J A Holroyd, E G Evans.   

Abstract

The mechanism of quercetin oxygenation, which is formally analogous to haem degradation, was studied by using 18O labelling. In both the enzymic oxygenation (catalysed by quercetinase) and the non-enzymic reaction (base-catalysed), both oxygen atoms incorporated into product were derived from a single oxygen molecule. Quercetin oxygenation therefore occurs by a classical dioxygenase mechanism and is not an appropriate model for study of the mechanism of haem catabolism.

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Year:  1982        PMID: 7126180      PMCID: PMC1158469          DOI: 10.1042/bj2050239

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  9 in total

Review 1.  The enzymatic formation of bilirubin.

Authors:  R Schmid; A F McDonagh
Journal:  Ann N Y Acad Sci       Date:  1975-04-15       Impact factor: 5.691

2.  Degradation of rutin by Aspergillus flavus. Purification and characterization of rutinase.

Authors:  G W HAY; D W WESTLAKE; F J SIMPSON
Journal:  Can J Microbiol       Date:  1961-12       Impact factor: 2.419

3.  Microbiol decomposition of rutin.

Authors:  D W WESTLAKE; G TALBOT; E R BLAKLEY; F J SIMPSON
Journal:  Can J Microbiol       Date:  1959-12       Impact factor: 2.419

4.  Production of carbon monoxide in the enzymatic degradation of rutin.

Authors:  F J SIMPSON; G TALBOT; D W WESTLAKE
Journal:  Biochem Biophys Res Commun       Date:  1960-01       Impact factor: 3.575

5.  Degradation of rutin by Aspergillus flavus. Studies with oxygen 18 on the action of a dioxygenase on quercetin.

Authors:  H G Krishnamurty; F J Simpson
Journal:  J Biol Chem       Date:  1970-03-25       Impact factor: 5.157

6.  Degradation of rutin by Aspergillus flavus. Purification of the dioxygenase, querecentinase.

Authors:  T Oka; F J Simpson; J J Child; C Mills
Journal:  Can J Microbiol       Date:  1971-01       Impact factor: 2.419

7.  The mechanism of haem catabolism. A study of haem breakdown in spleen microsomal fraction and in a model system by 18O labelling and metal substitution.

Authors:  R F King; S B Brown
Journal:  Biochem J       Date:  1978-07-15       Impact factor: 3.857

8.  Mechanism of bile-pigment synthesis in algae. 18O incorporation into phycocyanobilin in the unicellular rhodophyte, Cyanidium caldarium.

Authors:  S B Brown; A J Holroyd; R F Troxler
Journal:  Biochem J       Date:  1980-08-15       Impact factor: 3.857

9.  The mechanism of haem catabolism. Bilirubin formation in living rats by [18O]oxygen labelling.

Authors:  S B Brown; R F King
Journal:  Biochem J       Date:  1978-02-15       Impact factor: 3.857

  9 in total
  5 in total

Review 1.  Formation and Cleavage of C-C Bonds by Enzymatic Oxidation-Reduction Reactions.

Authors:  F Peter Guengerich; Francis K Yoshimoto
Journal:  Chem Rev       Date:  2018-06-22       Impact factor: 60.622

2.  Nitrosyl hydride (HNO) replaces dioxygen in nitroxygenase activity of manganese quercetin dioxygenase.

Authors:  Murugaeson R Kumar; Adrian Zapata; Alejandro J Ramirez; Sara K Bowen; Wilson A Francisco; Patrick J Farmer
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-14       Impact factor: 11.205

3.  Identification of the products of oxidation of quercetin by air oxygen at ambient temperature.

Authors:  Igor G Zenkevich; Anna Yu Eshchenko; Svetlana V Makarova; Alexander G Vitenberg; Yuri G Dobryakov; Viktor A Utsal
Journal:  Molecules       Date:  2007-03-27       Impact factor: 4.411

Review 4.  Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers.

Authors:  Daniela Buongiorno; Grit D Straganz
Journal:  Coord Chem Rev       Date:  2013-01-15       Impact factor: 22.315

5.  Laccase-Mediated Enhancement of the Antioxidant Activity of Propolis and Poplar Bud Exudates.

Authors:  Lorenzo Botta; Fabrizio Brunori; Antonia Tulimieri; Davide Piccinino; Roberta Meschini; Raffaele Saladino
Journal:  ACS Omega       Date:  2017-06-06
  5 in total

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