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Literature DB >> 7126170

Failure of leucine to stimulate protein synthesis in vivo.

Abstract

The effect of 100 mumol of leucine on protein synthesis in several tissues was assessed in the intact rat. Leucine had no immediate effect on protein synthesis in gastrocnemius muscle, heart, jejunal serosa, jejunal mucosa or liver in rats which were fed, starved for 2 days or deprived of dietary protein for 9 days. Leucine treatment for 1 h also failed to stimulate protein synthesis in tissues of 2-day-starved animals.

Entities: Chemical Species

Mesh：

Substances：
Muscle Proteins
Leucine

Year: 1982 PMID： 7126170 PMCID： PMC1158427 DOI： 10.1042/bj2040831

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

29 in total

1. Tritosol: a new scintillation cocktail based on Triton X-100.

Authors: U Fricke
Journal: Anal Biochem Date: 1975-02 Impact factor: 3.365

2. Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm.

Authors: R M Fulks; J B Li; A L Goldberg
Journal: J Biol Chem Date: 1975-01-10 Impact factor: 5.157

3. Effects of noncarbohydrate substrates on protein synthesis in muscle.

Authors: D E Rannels; A C Hjalmarson; H E Morgan
Journal: Am J Physiol Date: 1974-03

4. Suppression of protein turnover by amino acids in the perfused rat liver.

Authors: K H Woodside; G E Mortimore
Journal: J Biol Chem Date: 1972-10-25 Impact factor: 5.157

Review 5. Some special kinetic problems of transport.

Authors: H N Christensen
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1969

6. Coated charcoal immunoassay of insulin.

Authors: V Herbert; K S Lau; C W Gottlieb; S J Bleicher
Journal: J Clin Endocrinol Metab Date: 1965-10 Impact factor: 5.958

7. Control of protein synthesis in mammalian tissues through changes in ribosome activity.

Authors: E C Henshaw; C A Hirsch; B E Morton; H H Hiatt
Journal: J Biol Chem Date: 1971-01-25 Impact factor: 5.157

8. Leucine. A possible regulator of protein turnover in muscle.

Authors: M G Buse; S S Reid
Journal: J Clin Invest Date: 1975-11 Impact factor: 14.808

9. The diurnal response of muscle and liver protein synthesis in vivo in meal-fed rats.

Authors: P J Garlick; D J Millward; W P James
Journal: Biochem J Date: 1973-12 Impact factor: 3.857

10. The effect of protein deprivation and starvation on the rate of protein synthesis in tissues of the rat.

Authors: P J Garlick; D J Millward; W P James; J C Waterlow
Journal: Biochim Biophys Acta Date: 1975-11-18

18 in total

1. Amino acid flooding doses for measuring rates of protein synthesis.

Authors: A L Schaefer; S L Scott
Journal: Amino Acids Date: 1993-02 Impact factor: 3.520

Review 2. Regulation of protein turnover in skeletal and cardiac muscle.

Authors: P H Sugden; S J Fuller
Journal: Biochem J Date: 1991-01-01 Impact factor: 3.857

3. Future of enteral nutrition.

Authors: D B Silk
Journal: Gut Date: 1986-11 Impact factor: 23.059

4. Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin. Effect of branched-chain amino acids.

Authors: P J Garlick; I Grant
Journal: Biochem J Date: 1988-09-01 Impact factor: 3.857

5. Short-term effects of corticosterone treatment on muscle protein synthesis in relation to the response to feeding.

Authors: P J Garlick; I Grant; R T Glennie
Journal: Biochem J Date: 1987-12-01 Impact factor: 3.857

6. The role of insulin, corticosterone and other factors in the acute recovery of muscle protein synthesis on refeeding food-deprived rats.

Authors: D J Millward; B Odedra; P C Bates
Journal: Biochem J Date: 1983-12-15 Impact factor: 3.857