[Steroid-responsive nephrotic syndrome in infants: 2 familial case reports ].

Two cases of nephrotic syndrome discovered respectively at the ages of 3 and 7 weeks in 2 siblings are reported. Nephrosis was of the optically normal glomeruli-type in both cases. In spite of the very young age of the patients a good result of steroid-therapy was obtained after 6 and 8 weeks of treatment, respectively. Both children were not HLA-identical but had in common the A2-B12-DR4 haplotype.