| Literature DB >> 7125629 |
N L Humphries, D G Tasker, S J Karran.
Abstract
The biliary excretion of six cephalosporins was examined in normal and partially hepatectomized rats. Cefamandole, cefazolin, cefuroxime, cefoxitin, and cephradine were excreted well in normal animals. In partially hepatectomized rats, the cumulative percentage of excretion reached only 11 to 36.8% of the control levels. Cephaloridine was excreted poorly in both groups.Entities:
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Year: 1982 PMID： 7125629 PMCID： PMC183697 DOI： 10.1128/AAC.22.1.170
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191