Literature DB >> 7124246

The toxic A-chain of mistletoe lectin I: isolation and its effect on cell-free protein synthesis.

H Franz, A Kindt, P Ziska, H Bielka, R Benndorf, L Venker.   

Abstract

The reduction of Sepharose bound mistletoe lectin I (ML I) is a convenient method for preparing A- and B-chains under mild conditions. The B-chain represents the D-galactose binding moiety. The A-chain shows a significant dose-dependent inhibition of protein synthesis in cell-free systems from rat liver and rabbit reticulocytes, while pure B-chain preparations do not affect ribosomal translation processes.

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Year:  1982        PMID: 7124246

Source DB:  PubMed          Journal:  Acta Biol Med Ger        ISSN: 0001-5318


  2 in total

1.  Induction of tumor necrosis factor expression by a lectin from Viscum album.

Authors:  D N Männel; H Becker; A Gundt; A Kist; H Franz
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

2.  Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses.

Authors:  M Twardziok; D Meierhofer; S Börno; B Timmermann; S Jäger; Sengül Boral; A Eggert; C I Delebinski; G Seifert
Journal:  BMC Complement Altern Med       Date:  2017-04-28       Impact factor: 3.659

  2 in total

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