Literature DB >> 7119444

Monoclonal antibodies to human alpha-interferon and their use for affinity chromatography.

D Novick, Z Eshhar, M Rubinstein.   

Abstract

A new screening procedure has been developed and used for the identification of three hybridomas secreting monoclonal antibodies to human leukocyte interferon (IFN-alpha). The screening procedure is based on immune precipitation with a second antibody, acid dissociation of the precipitate, and bioassay of the recovered interferon. This procedure selects for monoclonal antibodies that are suitable for affinity chromatography, as demonstrated by construction of immunoadsorbents from these monoclonal antibodies and purification to homogeneity in IFN-alpha.

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Year:  1982        PMID： 7119444

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  10 in total

1.  Double-antibody sandwich enzyme-linked immunosorbent assay for cellobiohydrolase I.

Authors:  F J Riske; D E Eveleigh; J D Macmillan
Journal:  Appl Environ Microbiol       Date:  1990-11       Impact factor: 4.792

2.  Recessive genetic deregulation abrogates c-myc suppression by interferon and is implicated in oncogenesis.

Authors:  A Kimchi; D Resnitzky; R Ber; G Gat
Journal:  Mol Cell Biol       Date:  1988-07       Impact factor: 4.272

3.  Localization of interferons and interleukin 2 in polymyositis and muscular dystrophy.

Authors:  D A Isenberg; D Rowe; M Shearer; D Novick; P C Beverley
Journal:  Clin Exp Immunol       Date:  1986-02       Impact factor: 4.330

4.  HLA class I and II, interferon, interleukin 2, and the interleukin 2 receptor expression on labial biopsy specimens from patients with Sjögren's syndrome.

Authors:  D Rowe; M Griffiths; J Stewart; D Novick; P C Beverley; D A Isenberg
Journal:  Ann Rheum Dis       Date:  1987-08       Impact factor: 19.103

5.  3' end structure of the human (2'-5') oligo A synthetase gene: prediction of two distinct proteins with cell type-specific expression.

Authors:  P Benech; G Merlin; M Revel; J Chebath
Journal:  Nucleic Acids Res       Date:  1985-02-25       Impact factor: 16.971

6.  Molecular cloning and sequence of partial cDNA for interferon-induced (2'-5')oligo(A) synthetase mRNA from human cells.

Authors:  G Merlin; J Chebath; P Benech; R Metz; M Revel
Journal:  Proc Natl Acad Sci U S A       Date:  1983-08       Impact factor: 11.205

7.  The nature of neutralization reaction between effector protein and monoclonal antibody: a quantitative study of neutralization characteristics of anti-interferon antibodies.

Authors:  Y Kawade; Y Watanabe
Journal:  Immunology       Date:  1985-11       Impact factor: 7.397

8.  Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein.

Authors:  T Hahn; L Toker; S Budilovsky; D Aderka; Z Eshhar; D Wallach
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

9.  Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

Authors:  A Zilberstein; R Ruggieri; J H Korn; M Revel
Journal:  EMBO J       Date:  1986-10       Impact factor: 11.598

10.  Monoclonal antibodies to human interferon-gamma: production, affinity purification and radioimmunoassay.

Authors:  D Novick; Z Eshhar; D G Fischer; J Friedlander; M Rubinstein
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
  10 in total

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