Literature DB >> 711930

Displacement of bilirubin from albumin by indomethacin.

L F Rasmussen, C E Ahlfors, R P Wennberg.   

Abstract

The primary albumin binding site of indomethacin is remote from the bilirubin binding site. Indomethacin is, at most, a weak displacer of bilirubin at low serum drug concentrations. When administered at dosages less than 1 mg/kg, indomethacin would appear to be safe with respect to serum binding of bilirubin in premature infants.

Entities:  

Mesh:

Substances:

Year:  1978        PMID: 711930     DOI: 10.1002/j.1552-4604.1978.tb01575.x

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN: 0091-2700            Impact factor:   3.126


  6 in total

1.  Management of hyperbilirubinemia and prevention of kernicterus in 20 patients with Crigler-Najjar disease.

Authors:  Kevin A Strauss; Donna L Robinson; Hendrik J Vreman; Erik G Puffenberger; Graham Hart; D Holmes Morton
Journal:  Eur J Pediatr       Date:  2006-01-25       Impact factor: 3.183

2.  Neonatal pharmacology--a practical approach.

Authors:  D A MacKintosh
Journal:  Indian J Pediatr       Date:  1986 Jan-Feb       Impact factor: 1.967

3.  Effectiveness and pharmacokinetics of indomethacin in premature newborns with patent ductus arteriosus.

Authors:  P Vert; G Bianchetti; F Marchal; P Monin; P L Morselli
Journal:  Eur J Clin Pharmacol       Date:  1980-07       Impact factor: 2.953

Review 4.  Pharmacokinetics of common analgesics, anti-inflammatories and antipyretics in children.

Authors:  P D Walson; M E Mortensen
Journal:  Clin Pharmacokinet       Date:  1989       Impact factor: 6.447

5.  Influence of clinical status on the association between plasma total and unbound bilirubin and death or adverse neurodevelopmental outcomes in extremely low birth weight infants.

Authors:  W Oh; D K Stevenson; J E Tyson; B H Morris; C E Ahlfors; G Jesse Bender; R J Wong; R Perritt; B R Vohr; K P Van Meurs; H J Vreman; A Das; D L Phelps; T Michael O'Shea; R D Higgins
Journal:  Acta Paediatr       Date:  2010-01-25       Impact factor: 2.299

6.  Crystallographic analysis of human serum albumin complexed with 4Z,15E-bilirubin-IXalpha.

Authors:  Patricia A Zunszain; Jamie Ghuman; Antony F McDonagh; Stephen Curry
Journal:  J Mol Biol       Date:  2008-06-12       Impact factor: 5.469

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.