Literature DB >> 7119119

Basic isoferritin and hypercalcaemia in renal cell carcinoma.

G J Mufti, T J Hamblin, J Stevens.   

Abstract

A 63-year-old man with iron loss anaemia and hypercalcaemia was found to have a renal cell carcinoma. Despite the iron-deficient blood and bone marrow picture, the serum ferritin concentration was markedly raised. This was mainly due to a "basic isoferritin". The serum parathormone concentration was normal. The serum ferritin and calcium concentrations returned to normal after the tumour was removed. We propose that the renal cell carcinoma cells in this patient secreted the basic isoferritin as well as humoral factor(s) responsible for hypercalcaemia.

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Year:  1982        PMID： 7119119      PMCID： PMC497852          DOI： 10.1136/jcp.35.9.1008

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  17 in total

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Authors:  J W Drysdale; T G Adelman; P Arosio; D Casareale; P Fitzpatrick; J T Harzard; M Yokota
Journal:  Semin Hematol       Date:  1977-01       Impact factor: 3.851

2.  Carcino-foetal human liver ferritins.

Authors:  E Alpert; R L Coston; J W Drysdale
Journal:  Nature       Date:  1973-03-16       Impact factor: 49.962

3.  Carcinofetal human isoferritins in placenta and Hela cells.

Authors:  J W Drysdale; R M Singer
Journal:  Cancer Res       Date:  1974-12       Impact factor: 12.701

4.  Ferritin synthesis in normal and leukaemic leukocytes.

Authors:  G P White; M Worwood; D H Parry; A Jacobs
Journal:  Nature       Date:  1974-08-16       Impact factor: 49.962

5.  Synthesis and release of parathyroid hormone by a renal carcinoma in cell culture.

Authors:  P B Greenberg; T J Martin; H S Sutcliffe
Journal:  Clin Sci Mol Med       Date:  1973-08

6.  Ferritinaemia in cancer.

Authors:  J T Hazard; J W Drysdale
Journal:  Nature       Date:  1977-02-24       Impact factor: 49.962

7.  The purification and properties of ferritin from human serum.

Authors:  M Worwood; S Dawkins; M Wagstaff; A Jacobs
Journal:  Biochem J       Date:  1976-07-01       Impact factor: 3.857

8.  Human isoferritins: organ specific iron and apoferritin distribution.

Authors:  L W Powell; E Alpert; K J Isselbacher; J W Drysdale
Journal:  Br J Haematol       Date:  1975-05       Impact factor: 6.998

9.  An immunoradiometric assay for the acidic ferritin of human heart: application to human tissues, cells and serum.

Authors:  B M Jones; M Worwood
Journal:  Clin Chim Acta       Date:  1978-04-03       Impact factor: 3.786

10.  Prostaglandins as mediators of hypercalcemia associated with certain types of cancer.

Authors:  H W Seyberth; G V Segre; J L Morgan; B J Sweetman; J T Potts; J A Oates
Journal:  N Engl J Med       Date:  1975-12-18       Impact factor: 91.245
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  1 in total

1.  Tissue ferritin concentration and prognosis in carcinoma of the breast.

Authors:  R E Weinstein; B H Bond; B K Silberberg; C B Vaughn; P Subbaiah; D R Pieper
Journal:  Breast Cancer Res Treat       Date:  1989-12       Impact factor: 4.872
  1 in total

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