Literature DB >> 7118950

Steady flow in a model of the human carotid bifurcation. Part I--flow visualization.

B K Bharadvaj, R F Mabon, D P Giddens.   

Abstract

The geometry of a typical adult human carotid bifurcation, complete with the sinus, was established from a study of a large number of angiograms. A rigid model was constructed from glass and investigations were performed under steady flow conditions using flow visualization techniques over a range of upstream Reynolds numbers and flow division ratios through the branches representative of physiologic conditions expected in the human vasculature. The study reveals a complex flow field in which secondary flows play an important role. The separation regions occurring at the outer corners of the branching are also subjected to much higher shear stress. Comparison with pathologic data on localization of atherosclerotic lesions indicates that zones susceptible to disease experience low or oscillatory shear stress while regions subject to higher shear are free of deposits.

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Year:  1982        PMID: 7118950     DOI: 10.1016/0021-9290(82)90057-4

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  27 in total

1.  Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions.

Authors:  Yoram Richter; Adam Groothuis; Philip Seifert; Elazer R Edelman
Journal:  J Clin Invest       Date:  2004-06       Impact factor: 14.808

Review 2.  Intra-arterial delivery of cell therapies for stroke.

Authors:  Vivek Misra; Aditya Lal; Ramy El Khoury; Peng R Chen; Sean I Savitz
Journal:  Stem Cells Dev       Date:  2012-02-15       Impact factor: 3.272

3.  An improved real-time endovascular guidewire position simulation using shortest path algorithm.

Authors:  Jianpeng Qiu; Zhiyi Qu; Haiquan Qiu; Xiaomin Zhang
Journal:  Med Biol Eng Comput       Date:  2015-10-15       Impact factor: 2.602

4.  Nitric oxide is significantly reduced in ex vivo porcine arteries during reverse flow because of increased superoxide production.

Authors:  X Lu; G S Kassab
Journal:  J Physiol       Date:  2004-10-07       Impact factor: 5.182

5.  In vivo study of flow pattern at human carotid bifurcation with regard to aneurysm development.

Authors:  C Kim; J Cervós-Navarro; C Pätzold; Y Tokuriki; Y Takebe; K Hori
Journal:  Acta Neurochir (Wien)       Date:  1992       Impact factor: 2.216

6.  Real-time endovascular guidewire position simulation using shortest path algorithms.

Authors:  Sebastian Schafer; Vikas Singh; Peter B Noël; Alan M Walczak; Jinhui Xu; Kenneth R Hoffmann
Journal:  Int J Comput Assist Radiol Surg       Date:  2009-07-18       Impact factor: 2.924

7.  Evaluation of guidewire path reproducibility.

Authors:  Sebastian Schafer; Kenneth R Hoffmann; Peter B Noël; Ciprian N Ionita; Jacek Dmochowski
Journal:  Med Phys       Date:  2008-05       Impact factor: 4.071

8.  Characterization of coherent structures in the cardiovascular system.

Authors:  Shawn C Shadden; Charles A Taylor
Journal:  Ann Biomed Eng       Date:  2008-04-25       Impact factor: 3.934

9.  An experimental and angiographic explanation of why ulcerated carotid bulbs embolize.

Authors:  S G Imbesi; C W Kerber
Journal:  Interv Neuroradiol       Date:  2001-05-15       Impact factor: 1.610

10.  Numerical blood flow analysis: arterial bifurcation with a saccular aneurysm.

Authors:  K Perktold; T Kenner; D Hilbert; B Spork; H Florian
Journal:  Basic Res Cardiol       Date:  1988 Jan-Feb       Impact factor: 17.165

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