Clinical ERG findings in tobacco-alcohol amblyopia.

Eight patients with tobacco-alcohol amblyopia, but no significant changes in ERG configuration, were subjected to a more extended ERG analysis applying normalized a- and b-wave amplitude-intensity relationships. The functions established significantly fell out of the range of normal subjects, with respect to the maximum of the b-wave function in dark and light adaptation. In this way, the ERG discrimination level in detecting retinal disturbances in tobacco-alcohol amblyopia can be shifted towards higher sensitivity.