The cingulate cortex and gastric pathology.

Bilateral lesions in the anterior or posterior cingulate cortex were performed in rats. After a recovery period, the rats were immobilized for 24 hours. Results showed that posterior lesions increased the severity of the stomach pathology under restraint and non-restraint conditions. Anterior lesions, on the other hand, attenuated the effects of immobilization on gastric pathology. The data were discussed in reference to telencephalic limbic mechanisms and stress.