Literature DB >> 7115774

Effects of L-alanine on ketogenesis in vitro.

M C Sugden, D I Watts.   

Abstract

Alanine (5 mM) increased 14CO2 production from [1-14C]oleate by 130% and from [1-14C]butyrate by 101%. Alanine inhibited ketone-body production by 37.5% in the presence of butyrate but did not affect ketogenesis in the presence of oleate. Alanine decreased the [3-hydroxybutyrate]/[acetoacetate] ratio when either butyrate or oleate was present. The results are discussed with reference to the hypoketonaemic action of alanine in vivo.

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Year:  1982        PMID: 7115774     DOI: 10.1016/0304-4165(82)90193-3

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  3 in total

1.  Comparison of the effects of various amino acids on glycogen synthesis, lipogenesis and ketogenesis in isolated rat hepatocytes.

Authors:  A Baquet; A Lavoinne; L Hue
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

2.  Beta-adrenergic blockade restores glucose's antiketogenic activity after exercise in carbohydrate-depleted athletes.

Authors:  J H Adams; G Irving; J H Koeslag; J D Lochner; R C Sandell; C Wilkinson
Journal:  J Physiol       Date:  1987-05       Impact factor: 5.182

3.  Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans.

Authors:  J H Koeslag; L I Levinrad; J D Lochner; A A Sive
Journal:  J Physiol       Date:  1985-01       Impact factor: 5.182

  3 in total

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