Literature DB >> 7115452

Chronic arthritis of rabbits induced by mycoplasmas. III. Induction with nonviable Mycoplasma arthritidis antigens.

L R Washburn, B C Cole, J R Ward.   

Abstract

Preexposure of rabbits to Mycoplasma arthritidis predisposed them to subsequent development of chronic inflammation in knee joints challenged with nonviable M arthritidis antigens. Rabbits sensitized by hyperimmunization developed a more severe arthritis than those sensitized by infection. Unsensitized rabbits responded minimally to intraarticular injection of nonviable organisms. These results suggested that an immune response to a persisting mycoplasmal antigen might be capable of sustaining chronic inflammation in rabbits with arthritis induced by viable M arthritidis.

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Year:  1982        PMID： 7115452     DOI： 10.1002/art.1780250805

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  6 in total

1.  Comparison of four Mycoplasma arthritidis strains by enzyme immunoassay, metabolism inhibition, one- and two-dimensional electrophoresis, and immunoblotting.

Authors:  L R Washburn; S Hirsch
Journal:  J Clin Microbiol       Date:  1990-09       Impact factor: 5.948

Review 2.  Experimental animal models resembling rheumatoid arthritis.

Authors:  P M Kaklamanis
Journal:  Clin Rheumatol       Date:  1992-03       Impact factor: 2.980

3.  Strain differences in sensitivity of rats to Mycoplasma arthritidis ISR 1 infection are under multiple gene control.

Authors:  A Binder; K Gärtner; H J Hedrich; W Hermanns; H Kirchhoff; K Wonigeit
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

4.  I-E/I-C region-associated induction of murine gamma interferon by a haplotype-restricted polyclonal T-cell mitogen derived from Mycoplasma arthritidis.

Authors:  B C Cole; R N Thorpe
Journal:  Infect Immun       Date:  1984-01       Impact factor: 3.441

5.  Toxicity but not arthritogenicity of Mycoplasma arthritidis for mice associates with the haplotype expressed at the major histocompatibility complex.

Authors:  B C Cole; R N Thorpe; L A Hassell; L R Washburn; J R Ward
Journal:  Infect Immun       Date:  1983-09       Impact factor: 3.441

6.  Effect of Mycoplasma arthritidis superantigen on enzymatically induced arthritis in mice.

Authors:  H Sustackova; C A Chambers; N Hozumi; R A Kandel; P A Quinn; T F Cruz
Journal:  Clin Exp Immunol       Date:  1995-03       Impact factor: 4.330
  6 in total

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