Literature DB >> 7114975

The effects of nifedipine and verapamil on spontaneous and carbachol-stimulated contractions of rat urinary bladder "in vivo".

C A Maggi, G Grimaldi, A Meli.   

Abstract

The effects of nifedipine and verapamil on spontaneous and carbachol-induced contractions of rat urinary bladder have been studied after intravenous administration. Both nifedipine and verapamil delayed the onset of spontaneous contractions in a dose-dependent manner, but nifedipine on the contrary of verapamil only slightly antagonized the intensity of spontaneous contractions and of carbachol contracture. These results suggest that the effects of verapamil on rat urinary bladder "in vivo" are different from those of nifedipine.

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Year:  1982        PMID: 7114975

Source DB:  PubMed          Journal:  Arch Int Pharmacodyn Ther        ISSN: 0003-9780


  4 in total

1.  The effect of nifedipine and verapamil on KC1-induced rhythmic contractions of guinea pig ureter in vitro.

Authors:  C A Maggi; A Meli
Journal:  Experientia       Date:  1984-07-15

2.  Comparison of Bay K 8644, nitrendipine and atropine on spontaneous and pelvic-nerve-induced bladder contractions on rat bladder in vivo.

Authors:  W Diederichs; J Sroka; J Graff
Journal:  Urol Res       Date:  1992

Review 3.  Purinergic signalling in the urinary tract in health and disease.

Authors:  Geoffrey Burnstock
Journal:  Purinergic Signal       Date:  2013-11-22       Impact factor: 3.765

4.  Phentolamine-induced rhythmic contractions in bladder detrusor muscle of guinea-pig.

Authors:  N Satake; S Shibata; S Ueda
Journal:  Br J Pharmacol       Date:  1984-12       Impact factor: 8.739

  4 in total

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