Long-term evaluation of the treatment of Menière's disease with betahistine HCl.

Long-term evaluation of patients treated continuously for a period of 12-14 years with betahistine HCl shows a success rates of more than 80%. Many of these patients had various other kinds of therapy before betahistine HCl treatment to no avail. It seems to us that betahistine HCl is only a basic long-term treatment which has no habituation and still is active in controlling Menière's disease even after a long-term period. Other drugs such as antihistamine, phenothiazines, vitamins and tranquilizers only produce a symptomatic treatment. Betahistine HCl produces no modification or effect on the evolution of deafness.