| Literature DB >> 7113717 |
N G Toremalm, K Josefsson, K Klementsson, I Lagergren.
Abstract
The effect of eight penicillins on the mucociliary activity of rabbit trachea was tested in vitro. Carbenicillin and ampicillin had a minor inhibitory effect. Penicillin G and V and pheneticillin were a little more ciliestatic. Propicillin, cloxacillin and dicloxacillin were most toxic. The mucociliary toxicity increased with increasing lipophilicity of the penicillins and correlated well with their known neurotoxic in vivo effects.Entities:
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Year: 1982 PMID： 7113717 DOI： 10.1111/j.1600-0773.1982.tb00998.x
Source DB: PubMed Journal: Acta Pharmacol Toxicol (Copenh) ISSN： 0001-6683