Literature DB >> 7108415

The proximodistal determination of skeletal parts in the developing chick leg.

D A Rowe, J F Fallon.   

Abstract

Currently the chick leg bud or its components are being used extensively to study questions in development. Although fate maps of the leg, similar to that developed by Saunders (1948) for the wing, have been available (Hampé, 1957 a, 1959), no study of the proximodistal sequence of the specification of leg structures exists. Such a sequence developed for the wing by removal of the apical ectodermal ridge at successive stages (Saunders, 1948; Summerbell, 1974), has proven useful to the study of wing development. In this paper, we present a similar proximodistal sequence for the chick leg including the same developmental stage range as that of the wing sequence.

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Year:  1982        PMID: 7108415

Source DB:  PubMed          Journal:  J Embryol Exp Morphol        ISSN: 0022-0752


  10 in total

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3.  In vivo inhibition of programmed cell death by local administration of FGF-2 and FGF-4 in the interdigital areas of the embryonic chick leg bud.

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6.  Formation of extra-digits induced by surgical removal of the apical ectodermal ridge of the chick embryo leg bud in the stages previous to the onset of interdigital cell death.

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9.  Interdigital cell death in the embryonic limb is associated with depletion of Reelin in the extracellular matrix.

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10.  Dbx2 regulation in limbs suggests interTAD sharing of enhancers.

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  10 in total

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