| Literature DB >> 7106176 |
B Resul, T Lewander, B Ringdahl, T Zetterström, R Dahlbom.
Abstract
Some of the central and peripheral effects of oxotremorine (OT) and its azetidine analogue, N-[4-azetidinyl)-2-butynyl]-2-pyrrolidone (BM 120), were compared in mice and rats. BM 120 was found to be about twice as potent as OT and to have a somewhat longer duration of action. All its effects were antagonized by pretreatment with atropine sulphate. BM 120 acted as powerful muscarinic agonist on the isolated guinea pig ileum.Entities:
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Year: 1982 PMID： 7106176 DOI： 10.1016/0014-2999(82)90056-5
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432