Literature DB >> 710616

Suppressive effect of 1,2-dibromo-3-chloropropane on human spermatogenesis.

G Potashnik, N Ben-Aderet, R Israeli, I Yanai-Inbar, I Sober.   

Abstract

Azoospermia was diagnosed in six factory workers who had been chronically exposed to 1,2-dibromo-3-chloropropane. Infertility was the presenting symptom in two patients and a decrease in libido or impotence characterized the others. Hormone studies revealed elevated plasma follicle-stimulating hormone levels and normal plasma luteinizing hormone and testosterone concentrations. Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells, and a normal appearance of a relatively increased number of Leydig cells.

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Year:  1978        PMID: 710616     DOI: 10.1016/s0015-0282(16)43580-6

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  13 in total

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