Literature DB >> 7101279

The effect of protamine on proteinuria and glomerular sclerosis in aminonucleoside nephropathy.

T Saito, K Yamakage, K Kurosawa, Y Kyogoku, T Furuyama, K Yoshinaga.   

Abstract

An administration of protamine sulfate combined with aminonucleoside of puromycin (AN) could produce in rats severe nephrotic syndrome and histological changes similar to focal glomerular sclerosis more distinctly than AN alone. This may be attributed to the action of protamine which seemed to enhance the effect of AN, causing polyanion loss at the glomerular basement membrane.

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Year:  1982        PMID: 7101279     DOI: 10.1620/tjem.136.461

Source DB:  PubMed          Journal:  Tohoku J Exp Med        ISSN: 0040-8727            Impact factor:   1.848


  1 in total

1.  Glomerular cells and macrophages in the progression of experimental focal and segmental glomerulosclerosis.

Authors:  K Matsumoto; R C Atkins
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

  1 in total

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