Literature DB >> 7099243

Preliminary studies on the carcinogenic effects of Penicillium roqueforti toxin (PR toxin) on rats.

L Polonelli, L Lauriola, G Morace.   

Abstract

Preliminary results on the carcinogenic activity of a mycotoxin of Penicillium roqueforti (PR toxin) are reported. A squamous epithelioma and a uterine sarcoma were histologically confirmed in 2 of 10 albino rats fed PR toxin in a relatively short time (449 and 551 days respectively). Only an adenocarcinoma was histologically proven within a control group of 10 rats in a significantly longer (931 days) time span.

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Year:  1982        PMID： 7099243     DOI： 10.1007/BF00442636

Source DB:  PubMed          Journal:  Mycopathologia        ISSN： 0301-486X            Impact factor:   2.574


  11 in total

1.  Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H.

Authors:  F Tashiro; K Hiral; Y Ueno
Journal:  Appl Environ Microbiol       Date:  1979-08       Impact factor: 4.792

2.  CARCINOGENIC ACTIVITY OF AFLATOXIN TO RATS.

Authors:  J BARNES; W H BUTLER
Journal:  Nature       Date:  1964-06-06       Impact factor: 49.962

3.  Carcinogenic studies on water-soluble polymers.

Authors:  W C HUEPER
Journal:  Pathol Microbiol (Basel)       Date:  1961

4.  [Spontaneous tumors of the cranial cavity and genital organs in Sprague-Dawley and Bethesda-Black rats].

Authors:  E SCHULZE
Journal:  Z Krebsforsch       Date:  1960

5.  Genetic effects of PR toxin in eukaryotic microorganisms.

Authors:  R Wei; T Ong; W Whong; D Frezza; G Bronzetti; E Zeiger
Journal:  Environ Mutagen       Date:  1979

6.  Mutagenicity of carcinogenic mycotoxins in Salmonella typhimurium.

Authors:  Y Ueno; K Kubota; T Ito; Y Nakamura
Journal:  Cancer Res       Date:  1978-03       Impact factor: 12.701

7.  Formation of a factor lethal for S. typhimurium TA1530 and TA1531 on incubation of aflatoxin B 1 with rat liver microsomes.

Authors:  R C Garner; E C Miller; J A Miller; J V Garner; R S Hanson
Journal:  Biochem Biophys Res Commun       Date:  1971-11-05       Impact factor: 3.575

Review 8.  Acute and chronic effects of aflatoxin on the liver of domestic and laboratory animals: a review.

Authors:  P M Newberne; W H Butler
Journal:  Cancer Res       Date:  1969-01       Impact factor: 12.701

9.  Studies on the PR toxin of Penicillium roqueforti.

Authors:  L Polonelli; G Morace; F delle Monache; R A Samson
Journal:  Mycopathologia       Date:  1978-12-29       Impact factor: 2.574

10.  DNA-attacking ability of carcinogenic mycotoxins in recombination-deficient mutant cells of Bacillus subtilis.

Authors:  Y Ueno; K Kubota
Journal:  Cancer Res       Date:  1976-02       Impact factor: 12.701
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  4 in total

1.  Genotoxic activity of some mycotoxins using the SOS chromotest.

Authors:  Y Auffray; P Boutibonnes
Journal:  Mycopathologia       Date:  1987-10       Impact factor: 2.574

2.  [Antibacterial and genotoxic properties of 33 mycotoxins].

Authors:  P Boutibonnes; Y Auffray; C Malherbe; W Kogbo; C Marais
Journal:  Mycopathologia       Date:  1984-08-30       Impact factor: 2.574

3.  Secondary Metabolites from Penicillium roqueforti, A Starter for the Production of Gorgonzola Cheese.

Authors:  Lisa Vallone; Alberto Giardini; Gabriella Soncini
Journal:  Ital J Food Saf       Date:  2014-09-11

Review 4.  PR Toxin - Biosynthesis, Genetic Regulation, Toxicological Potential, Prevention and Control Measures: Overview and Challenges.

Authors:  Manish K Dubey; Mohd Aamir; Manish S Kaushik; Saumya Khare; Mukesh Meena; Surendra Singh; Ram S Upadhyay
Journal:  Front Pharmacol       Date:  2018-03-29       Impact factor: 5.810
  4 in total

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